Daniel A. Rodrigues

123 St Stephen's Green, 2
Dublin, L, Ireland

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 30 publications

Fulfilling multiple roles in PROTAC design: The emerging potential of oligonucleotides.

Fulfilling multiple roles in PROTAC design: The emerging potential of oligonucleotides.

Journal: European journal of medicinal chemistry

Published: November 17, 2025

Design, Synthesis, and Biological Evaluation of Novel Triazine-Based Dual Histone Deacetylase/phosphatidylinositol 3-kinase Inhibitors for Breast Cancer Therapy.

Design, Synthesis, and Biological Evaluation of Novel Triazine-Based Dual Histone Deacetylase/phosphatidylinositol 3-kinase Inhibitors for Breast Cancer Therapy.

Journal: ChemMedChem

Published: November 17, 2025

Discovery of N‑Acylhydrazone Derivatives as ROCK Inhibitors: A Journey from Virtual Screening and Structure-Based De Novo Design to the Identification of ROCK2 Selective Inhibitors and Beyond.

Discovery of N‑Acylhydrazone Derivatives as ROCK Inhibitors: A Journey from Virtual Screening and Structure-Based De Novo Design to the Identification of ROCK2 Selective Inhibitors and Beyond.

Journal: ACS bio & med chem Au

Published: November 11, 2025

Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease.

Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease.

Journal: European journal of medicinal chemistry

Published: May 11, 2025

Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups.

Drug Discovery for Histone Deacetylase Inhibition: Past, Present and Future of Zinc-Binding Groups.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: March 16, 2025

Selective inhibition of HDAC6 by N-acylhydrazone derivative reduces the proliferation and induces senescence in carcinoma hepatocellular cells.

Selective inhibition of HDAC6 by N-acylhydrazone derivative reduces the proliferation and induces senescence in carcinoma hepatocellular cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: May 03, 2024

Click-Capable Phenanthriplatin Derivatives as Tools to Study Pt(II)-Induced Nucleolar Stress.

Click-Capable Phenanthriplatin Derivatives as Tools to Study Pt(II)-Induced Nucleolar Stress.

Journal: ACS chemical biology

Published: March 14, 2024

First-in-class metallo-PROTAC as an effective degrader of select Pt-binding proteins.

First-in-class metallo-PROTAC as an effective degrader of select Pt-binding proteins.

Journal: Chemical communications (Cambridge, England)

Published: October 04, 2023

Identification of a mechanism-based binding mode for a histone deacetylase 6 inhibitor.

Identification of a mechanism-based binding mode for a histone deacetylase 6 inhibitor.

Journal: Nature communications

Published: September 26, 2023

The path to venetoclax resistance is paved with mutations, metabolism, and more.

The path to venetoclax resistance is paved with mutations, metabolism, and more.

Journal: Science translational medicine

Published: December 08, 2022

Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC.

Histone Deacetylase 6 Inhibition Exploits Selective Metabolic Vulnerabilities in LKB1 Mutant, KRAS Driven NSCLC.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Published: August 16, 2022

Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases.

Design, Synthesis and Pharmacological Evaluation of Novel Conformationally Restricted N-arylpiperazine Derivatives Characterized as D2/D3 Receptor Ligands, Candidates for the Treatment of Neurodegenerative Diseases.

Journal: Biomolecules

Published: July 12, 2022

Showing 1-12 of 30

Last Updated: 09/26/2026