Last Updated: 09/26/2026
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Found 10 publications
Safety, Tolerability, Pharmacokinetics, Food Effect of Ribitol, and Its Effect on QTcF in Healthy Adults: First-in-Human, Randomized, Double-Blind (Sponsor Unblinded), Placebo-Controlled Studies.
Journal: Clinical pharmacology in drug development
Published: March 30, 2026
Recommendation of mavacamten posology by model-based analyses in adults with obstructive hypertrophic cardiomyopathy.
Journal: CPT: pharmacometrics & systems pharmacology
Published: December 01, 2023
Characterization of mavacamten pharmacokinetics in patients with hypertrophic cardiomyopathy to inform dose titration.
Journal: CPT: pharmacometrics & systems pharmacology
Published: December 01, 2023
Effects of Omeprazole and Verapamil on the Pharmacokinetics, Safety, and Tolerability of Mavacamten: Two Drug-Drug Interaction Studies in Healthy Participants.
Journal: Clinical pharmacology in drug development
Published: May 09, 2023
Drug-Drug Interaction Potential of Mavacamten with Oral Contraceptives: Results from a Clinical Pharmacokinetic Study and a Physiologically Based Pharmacokinetic Model.
Journal: Journal of clinical pharmacology
Published: April 03, 2023
First-in-Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers.
Journal: Clinical pharmacology in drug development
Published: January 18, 2019
Pharmacokinetics and pharmacodynamics of voxelotor (GBT440) in healthy adults and patients with sickle cell disease.
Journal: British journal of clinical pharmacology
Published: October 22, 2018
PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers.
Journal: Journal of clinical pharmacology
Published: April 21, 2016
Absence of QTc prolongation with betrixaban: a randomized, double-blind, placebo- and positive-controlled thorough ECG study.
Journal: Expert opinion on pharmacotherapy
Published: December 11, 2012
Showing 1-10 of 10
Last Updated: 09/26/2026