Last Updated: 09/26/2026
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Found 17 publications
Drug-drug interaction assessments of clinical transporter inhibition: Learnings from the Transporter Working Group of the International Consortium for Innovation and Quality in Pharmaceutical Development.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: November 14, 2025
Endogenous plasma riboflavin is not a viable BCRP biomarker in human.
Journal: Clinical and translational science
Published: September 09, 2024
Survey of Pharmaceutical Industry's Best Practices around In Vitro Transporter Assessment and Implications for Drug Development: Considerations from the International Consortium for Innovation and Quality for Pharmaceutical Development Transporter Working Group.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: October 25, 2023
Discovery of (R)-(3-fluoropyrrolidin-1-yl)(6-((5-(trifluoromethyl)pyridin-2-yl)oxy)quinolin-2-yl)methanone (ABBV-318) and analogs as small molecule Nav1.7/ Nav1.8 blockers for the treatment of pain.
Journal: Bioorganic & medicinal chemistry
Published: December 16, 2021
Quantitation of Plasma Membrane Drug Transporters in Kidney Tissue and Cell Lines Using a Novel Proteomic Approach Enabled a Prospective Prediction of Metformin Disposition.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: March 29, 2021
Prodrug Strategies to Improve the Solubility of the HCV NS5A Inhibitor Pibrentasvir (ABT-530).
Journal: Journal of medicinal chemistry
Published: September 04, 2020
Coproporphyrin I Can Serve as an Endogenous Biomarker for OATP1B1 Inhibition: Assessment Using a Glecaprevir/Pibrentasvir Clinical Study.
Journal: Clinical and translational science
Published: May 07, 2020
Discovery of 2-aminoisobutyric acid ethyl ester (AIBEE) phosphoramidate prodrugs for delivering nucleoside HCV NS5B polymerase inhibitors.
Journal: Bioorganic & medicinal chemistry letters
Published: October 21, 2019
Synthesis and evaluation of 2'-dihalo ribonucleotide prodrugs with activity against hepatitis C virus.
Journal: Bioorganic & medicinal chemistry
Published: October 01, 2019
Translation of In Vitro Transport Inhibition Studies to Clinical Drug-Drug Interactions for Glecaprevir and Pibrentasvir.
Journal: The Journal of pharmacology and experimental therapeutics
Published: February 06, 2019
No Inhibition of MATE1/2K-Mediated Renal Creatinine Secretion Predicted With Ritonavir or Cobicistat.
Journal: Journal of pharmaceutical sciences
Published: December 11, 2018
Mechanistic Physiologically Based Pharmacokinetic Modeling of the Dissolution and Food Effect of a Biopharmaceutics Classification System IV Compound-The Venetoclax Story.
Journal: Journal of pharmaceutical sciences
Published: July 24, 2017
Last Updated: 09/26/2026