Daniel Paape

Glasgow, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 17 publications

Novel Thienopyrimidine Inhibitors of Leishmania N-Myristoyltransferase with On-Target Activity in Intracellular Amastigotes.

Novel Thienopyrimidine Inhibitors of Leishmania N-Myristoyltransferase with On-Target Activity in Intracellular Amastigotes.

Journal: Journal of medicinal chemistry
Published: June 25, 2020

Leishmania Encodes a Bacterium-like 2,4-Dienoyl-Coenzyme A Reductase That Is Required for Fatty Acid β-Oxidation and Intracellular Parasite Survival.

Leishmania Encodes a Bacterium-like 2,4-Dienoyl-Coenzyme A Reductase That Is Required for Fatty Acid β-Oxidation and Intracellular Parasite Survival.

Journal: mBio
Published: June 04, 2020

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs.

Journal: PLoS pathogens
Published: June 01, 2020

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.

Journal: Nature microbiology
Published: March 20, 2020

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.

Journal: eLife
Published: February 26, 2020

Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model.

Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model.

Journal: Parasites & vectors
Published: July 29, 2019

Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages.

Cloning and functional complementation of ten Schistosoma mansoni phosphodiesterases expressed in the mammalian host stages.

Journal: PLoS neglected tropical diseases
Published: July 26, 2019

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection.

Changes to cholesterol trafficking in macrophages by Leishmania parasites infection.

Journal: MicrobiologyOpen
Published: October 04, 2016

Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei.

Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei.

Journal: ACS infectious diseases
Published: February 28, 2016

Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation.

Mapping replication dynamics in Trypanosoma brucei reveals a link with telomere transcription and antigenic variation.

Journal: eLife
Published: November 02, 2015

Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiation.

Diverged composition and regulation of the Trypanosoma brucei origin recognition complex that mediates DNA replication initiation.

Journal: Nucleic acids research
Published: November 02, 2015

Discovery of high affinity inhibitors of Leishmania donovani N-myristoyltransferase.

Discovery of high affinity inhibitors of Leishmania donovani N-myristoyltransferase.

Journal: MedChemComm
Published: June 06, 2015
Showing 1-12 of 17

Last Updated: 09/26/2026