Daniel Rauh

Dortmund, NW, Germany

Last Updated: 09/26/2026

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Found 114 publications

Nilotinib revisited in GIST: Salvage use in patients with severe imatinib toxicity.

Nilotinib revisited in GIST: Salvage use in patients with severe imatinib toxicity.

Journal: The oncologist

Published: March 27, 2026

Lessons from Structural Biology for Understanding Drug Resistance in Gastrointestinal Stromal Tumors (GIST).

Lessons from Structural Biology for Understanding Drug Resistance in Gastrointestinal Stromal Tumors (GIST).

Journal: Journal of medicinal chemistry

Published: March 02, 2026

Isoform-Selective Targeting of Akt Through Covalent Allosteric Inhibition.

Isoform-Selective Targeting of Akt Through Covalent Allosteric Inhibition.

Journal: Angewandte Chemie (International ed. in English)

Published: January 29, 2026

Structure-based scaffold hopping reveals strategies to overcome oncogenic KIT and PDGFRA mutation-driven drug-resistance in GIST.

Structure-based scaffold hopping reveals strategies to overcome oncogenic KIT and PDGFRA mutation-driven drug-resistance in GIST.

Journal: Nature communications

Published: December 08, 2025

Elimusertib enhances cytotoxic effects of conventional chemotherapy and sensitizes to radiation in preclinical Ewing sarcoma models.

Elimusertib enhances cytotoxic effects of conventional chemotherapy and sensitizes to radiation in preclinical Ewing sarcoma models.

Journal: Scientific reports

Published: October 16, 2025

Lipid Pocket Binders Impose Allosteric Changes of Protein Dynamics Around the Active Site of the Protein Kinase p38α.

Lipid Pocket Binders Impose Allosteric Changes of Protein Dynamics Around the Active Site of the Protein Kinase p38α.

Journal: Angewandte Chemie (International ed. in English)

Published: October 15, 2025

Computational Design of Lysine Targeting Covalent Binders Using Rosetta.

Computational Design of Lysine Targeting Covalent Binders Using Rosetta.

Journal: Journal of chemical information and modeling

Published: May 29, 2025

Targeting KRASG13C with cyclic linker based inhibitors to explore warhead orientation.

Targeting KRASG13C with cyclic linker based inhibitors to explore warhead orientation.

Journal: Scientific reports

Published: February 14, 2025

Phase II Trial of Ponatinib in Patients with Metastatic Gastrointestinal Stromal Tumor following Failure or Intolerance of Prior Therapy with Imatinib (POETIG Trial).

Phase II Trial of Ponatinib in Patients with Metastatic Gastrointestinal Stromal Tumor following Failure or Intolerance of Prior Therapy with Imatinib (POETIG Trial).

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: January 24, 2025

Design, Synthesis, and SAR of Covalent KIT and PDGFRA Inhibitors─Exploring Their Potential in Targeting GIST.

Design, Synthesis, and SAR of Covalent KIT and PDGFRA Inhibitors─Exploring Their Potential in Targeting GIST.

Journal: Journal of medicinal chemistry

Published: January 22, 2025

Advancing TET Inhibitor Development: From Structural Insights to Biological Evaluation.

Advancing TET Inhibitor Development: From Structural Insights to Biological Evaluation.

Journal: ACS medicinal chemistry letters

Published: January 22, 2025

Reply to Y. Xia et al.

Reply to Y. Xia et al.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Published: July 08, 2024

Showing 1-12 of 114

Last Updated: 09/26/2026