Daniel Weckbecker

Wendelsheim, RP, Germany

Last Updated: 09/26/2026

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Found 13 publications

A quantitative Lewy-fold-specific alpha-synuclein seed amplification assay as a progression marker for Parkinson's disease.

A quantitative Lewy-fold-specific alpha-synuclein seed amplification assay as a progression marker for Parkinson's disease.

Journal: Acta neuropathologica

Published: October 23, 2024

Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial.

Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial.

Journal: EBioMedicine

Published: September 17, 2021

[11C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates.

[11C]MODAG-001-towards a PET tracer targeting α-synuclein aggregates.

Journal: European journal of nuclear medicine and molecular imaging

Published: July 09, 2020

11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier.

11 C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier.

Journal: ChemMedChem

Published: December 12, 2019

Potential sources of interference with the highly sensitive detection and quantification of alpha-synuclein seeds by qRT-QuIC.

Potential sources of interference with the highly sensitive detection and quantification of alpha-synuclein seeds by qRT-QuIC.

Journal: FEBS open bio

Published: November 06, 2019

Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin.

Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin.

Journal: Biochimica et biophysica acta. Biomembranes

Published: June 07, 2019

Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression.

Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression.

Journal: Scientific reports

Published: June 19, 2018

Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy.

Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy.

Journal: Movement disorders : official journal of the Movement Disorder Society

Published: May 24, 2018

Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates.

Photophysics of diphenyl-pyrazole compounds in solutions and α-synuclein aggregates.

Journal: Biochimica et biophysica acta. General subjects

Published: August 23, 2017

Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies.

Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies.

Journal: Acta neuropathologica

Published: July 24, 2015

Methods to study the biogenesis of membrane proteins in yeast mitochondria.

Methods to study the biogenesis of membrane proteins in yeast mitochondria.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: September 03, 2013

Biogenesis of mitochondrial proteins.

Biogenesis of mitochondrial proteins.

Journal: Advances in experimental medicine and biology

Published: June 26, 2012

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Last Updated: 09/26/2026