Last Updated: 09/26/2026
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Found 62 publications
LRRK2 as a Potential Disease-Modifying Target in Sporadic Parkinson's Disease.
Journal: Movement disorders : official journal of the Movement Disorder Society
Published: April 11, 2025
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial.
Journal: Nature communications
Published: March 31, 2025
Biologically defined neuronal synuclein disease as a tool to advance drug development.
Journal: NPJ Parkinson's disease
Published: October 31, 2024
Neuronal alpha-Synuclein Disease Integrated Staging System performance in PPMI, PASADENA, and SPARK baseline cohorts.
Journal: medRxiv : the preprint server for health sciences
Published: September 24, 2024
LRRK2-Associated Parkinsonism With and Without In Vivo Evidence of Alpha-Synuclein Aggregates.
Journal: medRxiv : the preprint server for health sciences
Published: August 07, 2024
LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization.
Journal: Brain communications
Published: July 31, 2024
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research.
Journal: The Lancet. Neurology
Published: July 21, 2023
Clinical Characterization of [18F]T-008, a Cholesterol 24-Hydroxylase PET Ligand: Dosimetry, Kinetic Modeling, Variability, and Soticlestat Occupancy.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Published: April 20, 2023
LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease.
Journal: Movement disorders : official journal of the Movement Disorder Society
Published: August 07, 2022
Serial olfactory testing for the diagnosis of prodromal Parkinson's disease in the PARS study.
Journal: Parkinsonism & related disorders
Published: July 11, 2022
Last Updated: 09/26/2026