Dr. Danny Muehlschlegel

J. Danny Muehlschlegel, MD, MMSc, MBA, FAHA, FASA is an attending cardiovascular anesthesiologist at Johns Hopkins University School of Medicine, where he serves as the Director (Chair) of the Department of Anesthesiology and Critical Care Medicine. He is also a Professor of Anesthesiology and Critical Care Medicine at the Johns Hopkins School of Medicine and the Mark C. Rogers Professor. As a cardiac anesthesiologist with significant subspecialty training in all aspects of cardiac disease and transesophageal echocardiography, Dr. Muehlschlegel is a perioperative physician guiding the care of very sick patients with cardiovascular disease. Dr. Muehlschlegel is an NIH-funded physician-scientist with an active laboratory examining the impact of genetic variation upon adverse cardiovascular events and their significance on a functional level. He is the principal investigator of the CABG Genomics study group and the PI of the NHLBI-sponsored TRANSCRIBE (transcriptomic analysis of left ventricular gene expression) study. Both studies aim to determine the relationship between genetic variation and perioperative myocardial injury in patients undergoing cardiac surgery. Dr. Muehlschlegel is also the principal investigator of the NHLBI-sponsored GENEXPRO Surg (Gene Expression Profiling in Subjects with Postoperative Atrial Fibrillation after Cardiac Surgery) which aims to characterize the left atrium, the site in proximity to the origination of atrial fibrillation, using a multi ‘omics approach. Among his leadership roles, Muehlschlegel serves on the Board of Directors of the Society of Cardiovascular Anesthesiologists and is a member of the Association of University Anesthesiologists, the Association of Cardiac Anesthesiologists, and on the leadership committee of the American Heart Association’s Council on Cardiovascular Surgery and Anesthesia. He is also an associate oral board examiner of the American Board of Anesthesiology, which will allow him to contribute to, and have a national impact on the specialty of anesthesiology. Research Summary My research investigates the impact of genetic variation on adverse cardiovascular events and their functional significance. My cardiac anesthesia patients, possessing transcriptional upregulation, serve as research subjects, enabling genetic transcription variation analysis. I spearhead the CABG Genomics and TRANSCRIBE study groups, focusing on genetic variation's role in perioperative myocardial injury during cardiac surgery. I also manage the GENEXPRO Surg project, utilizing multi 'omics approaches to understand postoperative atrial fibrillation. As Chief Scientific Officer for Team Heart, I blend clinical cardiac anesthesia with genetic research, examining the genetics behind rheumatic heart disease in Rwanda through the RECHARGE study.

His clinical expertise encompasses Coronary Artery Bypass Graft (CABG) and Aortic Valve Replacement.

Dr. Muehlschlegel is board certified in American Board Of Anesthesiology and National Board Of Echocardiography. He is actively involved in clinical research, co-authoring 98 peer reviewed articles and participating in 4 clinical trials.