Darin W. Mcdonald

London, ON N6A3K7, Canada

Last Updated: 09/26/2026

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Found 13 publications

Mitochondrial respiration modulates Hsf1 activation and the heat shock response.

Mitochondrial respiration modulates Hsf1 activation and the heat shock response.

Journal: bioRxiv : the preprint server for biology
Published: May 25, 2026

Implications of Codon Usage, tRNA Gene Redundancy and tRNA Gene Clustering in Experimental Models of Mistranslation.

Implications of Codon Usage, tRNA Gene Redundancy and tRNA Gene Clustering in Experimental Models of Mistranslation.

Journal: Journal of molecular biology
Published: August 26, 2025

Progeria-based vascular model identifies networks associated with cardiovascular aging and disease.

Progeria-based vascular model identifies networks associated with cardiovascular aging and disease.

Journal: Aging cell
Published: July 12, 2023

Reduced USP22 Expression Impairs Mitotic Removal of H2B Monoubiquitination, Alters Chromatin Compaction and Induces Chromosome Instability That May Promote Oncogenesis.

Reduced USP22 Expression Impairs Mitotic Removal of H2B Monoubiquitination, Alters Chromatin Compaction and Induces Chromosome Instability That May Promote Oncogenesis.

Journal: Cancers
Published: December 04, 2020

DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks.

DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks.

Journal: Molecular and cellular biology
Published: July 14, 2016

Poly(ADP-ribosyl)ation-dependent Transient Chromatin Decondensation and Histone Displacement following Laser Microirradiation.

Poly(ADP-ribosyl)ation-dependent Transient Chromatin Decondensation and Histone Displacement following Laser Microirradiation.

Journal: The Journal of biological chemistry
Published: October 05, 2015

Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.

Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting.

Journal: ACS chemical biology
Published: April 25, 2015

The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice.

The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice.

Journal: Nature cell biology
Published: November 28, 2014

Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin.

Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin.

Journal: The Journal of cell biology
Published: October 09, 2013

A small molecule inhibitor of polycomb repressive complex 1 inhibits ubiquitin signaling at DNA double-strand breaks.

A small molecule inhibitor of polycomb repressive complex 1 inhibits ubiquitin signaling at DNA double-strand breaks.

Journal: The Journal of biological chemistry
Published: August 02, 2013

Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation.

Kdm4b histone demethylase is a DNA damage response protein and confers a survival advantage following γ-irradiation.

Journal: The Journal of biological chemistry
Published: June 08, 2013

A requirement for polymerized actin in DNA double-strand break repair.

A requirement for polymerized actin in DNA double-strand break repair.

Journal: Nucleus (Austin, Tex.)
Published: June 13, 2012
Showing 1-12 of 13

Last Updated: 09/26/2026