Dario Difrancesco

Milan, Italy

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 58 publications

Comprehensive classification of HCN1 variants linked to neurodevelopmental disorders with and without epilepsy.

Comprehensive classification of HCN1 variants linked to neurodevelopmental disorders with and without epilepsy.

Journal: bioRxiv : the preprint server for biology

Published: March 27, 2026

Combining elastic network models and linear response theory as tool to understand the global dynamics in allosteric regulation of HCN channels.

Combining elastic network models and linear response theory as tool to understand the global dynamics in allosteric regulation of HCN channels.

Journal: The Journal of general physiology

Published: September 23, 2025

AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic bradycardia.

AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic bradycardia.

Journal: The Journal of general physiology

Published: August 17, 2025

Extracellular activation of HCN4 by a subtype-specific nanobody.

Extracellular activation of HCN4 by a subtype-specific nanobody.

Journal: Nature communications

Published: February 12, 2025

Structure mirroring function: What's the 'matter' with the funny current?

Structure mirroring function: What's the 'matter' with the funny current?

Journal: The Journal of physiology

Published: November 06, 2024

Structural determinants of ivabradine block of the open pore of HCN4.

Structural determinants of ivabradine block of the open pore of HCN4.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 25, 2024

Missing validation of key features in HCN single-channel recordings.

Missing validation of key features in HCN single-channel recordings.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 08, 2024

A high affinity switch for cAMP in the HCN pacemaker channels.

A high affinity switch for cAMP in the HCN pacemaker channels.

Journal: Nature communications

Published: May 25, 2023

Silvio Weidmann: laying the foundations for unravelling the mechanism of heart rhythm.

Silvio Weidmann: laying the foundations for unravelling the mechanism of heart rhythm.

Journal: Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Published: May 01, 2023

Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block.

Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block.

Journal: The Journal of general physiology

Published: February 01, 2023

Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels.

Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels.

Journal: eLife

Published: October 29, 2021

Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy.

Discovery of Herbacetin as a Novel SGK1 Inhibitor to Alleviate Myocardial Hypertrophy.

Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Published: April 10, 2021

Showing 1-12 of 58

Last Updated: 09/26/2026