Dario R. Alessi

Dundee, SCT DD15EH, United Kingdom

Last Updated: 09/26/2026

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Found 157 publications

Retraction Note: Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.

Retraction Note: Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.

Journal: Scientific reports
Published: August 25, 2026

LRRK2 in Focus: A Global Browser Linking Genetic Diversity to Functional Effects.

LRRK2 in Focus: A Global Browser Linking Genetic Diversity to Functional Effects.

Journal: medRxiv : the preprint server for health sciences
Published: July 10, 2026

Large-scale functional annotation establishes a reference framework for human LRRK2 variants.

Large-scale functional annotation establishes a reference framework for human LRRK2 variants.

Journal: medRxiv : the preprint server for health sciences
Published: July 03, 2026

Elucidating the molecular interplay between LRRK2 and Rab GTPases.

Elucidating the molecular interplay between LRRK2 and Rab GTPases.

Journal: bioRxiv : the preprint server for biology
Published: May 18, 2026

Addressing the Challenges of Translating LRRK2 Biology into Disease-Modifying Therapies: The LRRK2 Investigative Therapeutics Exchange Initiative.

Addressing the Challenges of Translating LRRK2 Biology into Disease-Modifying Therapies: The LRRK2 Investigative Therapeutics Exchange Initiative.

Journal: Movement disorders : official journal of the Movement Disorder Society
Published: April 16, 2026

Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons.

Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons.

Journal: Nature communications
Published: February 20, 2026

Ex Vivo LRRK2 Activation in Asian G2385R and R1628P Variant Carriers and Idiopathic Parkinson's Disease.

Ex Vivo LRRK2 Activation in Asian G2385R and R1628P Variant Carriers and Idiopathic Parkinson's Disease.

Journal: Movement disorders : official journal of the Movement Disorder Society
Published: November 17, 2025

Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons.

Leucine-rich repeat kinase 2 impairs the release sites of Parkinson's disease vulnerable dopamine axons.

Journal: bioRxiv : the preprint server for biology
Published: September 05, 2025

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved TBM motif.

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved TBM motif.

Journal: bioRxiv : the preprint server for biology
Published: September 02, 2025

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif.

Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif.

Journal: Structure (London, England : 1993)
Published: August 19, 2025

NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress.

NRBP1 pseudokinase binds to and activates the WNK pathway in response to osmotic stress.

Journal: Science advances
Published: July 16, 2025

NRBP1 and TSC22D proteins affect distal convoluted tubule physiology through modulation of the WNK pathway.

NRBP1 and TSC22D proteins affect distal convoluted tubule physiology through modulation of the WNK pathway.

Journal: Science advances
Published: July 16, 2025
Showing 1-12 of 157

Last Updated: 09/26/2026