Darragh P. O'brien

Roosevelt Drive
Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 38 publications

Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.

Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.

Journal: Research square

Published: December 03, 2025

Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.

Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.

Journal: Signal transduction and targeted therapy

Published: November 09, 2025

Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles.

Tracking tau and cellular responses in human iPSC-microglia: from uptake to seedable secretion, including in extracellular vesicles.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association

Published: October 16, 2025

Driving Therapeutic Innovation in Neurodegenerative Disease With Hydrogen Deuterium eXchange Mass Spectrometry.

Driving Therapeutic Innovation in Neurodegenerative Disease With Hydrogen Deuterium eXchange Mass Spectrometry.

Journal: Molecular & cellular proteomics : MCP

Published: April 10, 2025

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor.

Journal: Journal of proteome research

Published: January 13, 2025

Nucleophagy removes cytotoxic trapped PARP1.

Nucleophagy removes cytotoxic trapped PARP1.

Journal: Nature cell biology

Published: September 10, 2024

Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.

Multi-omics analysis of a pig-to-human decedent kidney xenotransplant.

Journal: Nature

Published: July 22, 2024

Editorial: Beyond protein degradation and lysine modification: novel insights into non-canonical ubiquitination.

Editorial: Beyond protein degradation and lysine modification: novel insights into non-canonical ubiquitination.

Journal: Frontiers in molecular biosciences

Published: July 08, 2024

Imaging and video of late preterm delivery by midline laparotomy due to incarcerated uterus: A case report and literature review of a rare but morbid condition.

Imaging and video of late preterm delivery by midline laparotomy due to incarcerated uterus: A case report and literature review of a rare but morbid condition.

Journal: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Published: February 09, 2024

Rational discovery of therapeutic PAK1 allosteric activators.

Rational discovery of therapeutic PAK1 allosteric activators.

Journal: Cell

Published: January 27, 2024

Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.

Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease.

Journal: Nature neuroscience

Published: January 03, 2024

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.

USP16 is an ISG15 cross-reactive deubiquitinase that targets pro-ISG15 and ISGylated proteins involved in metabolism.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: December 06, 2023

Showing 1-12 of 38

Last Updated: 09/26/2026