David A. Fairman

Stevenage, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 13 publications

TMDD Modeling for Antibodies Directed Against Soluble Targets: Parameter Values for De Novo Modeling and Simulation From Experimental Data.

TMDD Modeling for Antibodies Directed Against Soluble Targets: Parameter Values for De Novo Modeling and Simulation From Experimental Data.

Journal: Clinical pharmacology and therapeutics
Published: November 25, 2025

Co-ordinated shifts in deep-water formation and Gulf Stream migration during abrupt climate changes.

Co-ordinated shifts in deep-water formation and Gulf Stream migration during abrupt climate changes.

Journal: Nature communications
Published: September 26, 2025

Best Practices in mAb and Soluble Target Assay Selection for Quantitative Modelling and Qualitative Interpretation.

Best Practices in mAb and Soluble Target Assay Selection for Quantitative Modelling and Qualitative Interpretation.

Journal: The AAPS journal
Published: September 22, 2022

Efficacy and safety of GSK3772847 in participants with moderate-to-severe asthma with allergic fungal airway disease: A phase IIa randomized, multicenter, double-blind, sponsor-open, comparative trial.

Efficacy and safety of GSK3772847 in participants with moderate-to-severe asthma with allergic fungal airway disease: A phase IIa randomized, multicenter, double-blind, sponsor-open, comparative trial.

Journal: PloS one
Published: August 23, 2022

Safety, tolerability, and pharmacokinetics of a single ascending subcutaneous dose of GSK3772847 in healthy participants.

Safety, tolerability, and pharmacokinetics of a single ascending subcutaneous dose of GSK3772847 in healthy participants.

Journal: Pharmacology research & perspectives
Published: July 26, 2022

Corrigendum to "Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling" [International Journal of Cardiology 167 (2013) 2630-2637].

Corrigendum to "Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling" [International Journal of Cardiology 167 (2013) 2630-2637].

Journal: International journal of cardiology
Published: April 03, 2022

Free Drug Theory - No Longer Just a Hypothesis?

Free Drug Theory - No Longer Just a Hypothesis?

Journal: Pharmaceutical research
Published: November 22, 2021

How translational modeling in oncology needs to get the mechanism just right.

How translational modeling in oncology needs to get the mechanism just right.

Journal: Clinical and translational science
Published: June 25, 2021

A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor.

A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ6 integrin inhibitor.

Journal: Respiratory research
Published: December 23, 2019

Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment.

Engineering of a GLP-1 analogue peptide/anti-PCSK9 antibody fusion for type 2 diabetes treatment.

Journal: Scientific reports
Published: August 10, 2018

Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants.

Safety, tolerability and pharmacokinetics of GSK3008348, a novel integrin αvβ6 inhibitor, in healthy participants.

Journal: European journal of clinical pharmacology
Published: November 17, 2017

Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.

Why has model-informed precision dosing not yet become common clinical reality? lessons from the past and a roadmap for the future.

Journal: Clinical pharmacology and therapeutics
Published: January 09, 2017
Showing 1-12 of 13

Last Updated: 09/26/2026