David A. Lane

London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 23 publications

Laminin G1 residues of protein S mediate its TFPI cofactor function and are competitively regulated by C4BP.

Laminin G1 residues of protein S mediate its TFPI cofactor function and are competitively regulated by C4BP.

Journal: Blood advances

Published: May 26, 2021

Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis.

Exosites in Hypervariable Loops of ADAMTS Spacer Domains control Substrate Recognition and Proteolysis.

Journal: Scientific reports

Published: May 14, 2019

Partial rescue of naturally occurring active site factor X variants through decreased inhibition by tissue factor pathway inhibitor and antithrombin.

Partial rescue of naturally occurring active site factor X variants through decreased inhibition by tissue factor pathway inhibitor and antithrombin.

Journal: Journal of thrombosis and haemostasis : JTH

Published: April 25, 2019

The roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complex.

The roles of factor Va and protein S in formation of the activated protein C/protein S/factor Va inactivation complex.

Journal: Journal of thrombosis and haemostasis : JTH

Published: March 06, 2019

Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant function.

Defective fibrin deposition and thrombus stability in Bambi-/- mice are mediated by elevated anticoagulant function.

Journal: Journal of thrombosis and haemostasis : JTH

Published: February 14, 2019

The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.

The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.

Journal: The European respiratory journal

Published: September 22, 2018

A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.

A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.

Journal: The Journal of biological chemistry

Published: January 28, 2018

Biphasic activation of complement and fibrinolysis during the human nasal allergic response.

Biphasic activation of complement and fibrinolysis during the human nasal allergic response.

Journal: The Journal of allergy and clinical immunology

Published: October 16, 2017

A common mechanism by which type 2A von Willebrand disease mutations enhance ADAMTS13 proteolysis revealed with a von Willebrand factor A2 domain FRET construct.

A common mechanism by which type 2A von Willebrand disease mutations enhance ADAMTS13 proteolysis revealed with a von Willebrand factor A2 domain FRET construct.

Journal: PloS one

Published: July 31, 2017

A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.

A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.

Journal: The Journal of biological chemistry

Published: January 13, 2017

Correcting the hemophilic imbalance.

Correcting the hemophilic imbalance.

Journal: Blood

Published: January 07, 2017

Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation.

Factor V has an anticoagulant cofactor activity that targets the early phase of coagulation.

Journal: The Journal of biological chemistry

Published: November 24, 2016

Showing 1-12 of 23

Last Updated: 09/26/2026