David A. Powell
210-887 Great Northern Way
Vancouver, BC V5T4T5, Canada
Vancouver, BC V5T4T5, Canada
Last Updated: 09/26/2026
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Found 8 publications
Characterization of CHK-336, A First-in-Class, Liver-Targeted, Small-Molecule Lactate Dehydrogenase Inhibitor for Hyperoxaluria Treatment.
Journal: Journal of the American Society of Nephrology : JASN
Published: October 21, 2024
Reducing the Toxicity of Designer Aminoglycosides as Nonsense Mutation Readthrough Agents for Therapeutic Targets.
Journal: ACS medicinal chemistry letters
Published: June 24, 2021
Dual Glycolate Oxidase/Lactate Dehydrogenase A Inhibitors for Primary Hyperoxaluria.
Journal: ACS medicinal chemistry letters
Published: April 07, 2021
In Vitro Assessment of Putative PD-1/PD-L1 Inhibitors: Suggestions of an Alternative Mode of Action.
In Vitro Assessment of Putative PD-1/PD-L1 Inhibitors: Suggestions of an Alternative Mode of Action.
Journal: ACS medicinal chemistry letters
Published: May 15, 2019
Correction to Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.
Journal: Journal of medicinal chemistry
Published: December 29, 2015
Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors.
Journal: Journal of medicinal chemistry
Published: September 24, 2015
An overview of patented small molecule stearoyl coenzyme-A desaturase inhibitors (2009 - 2013).
Journal: Expert opinion on therapeutic patents
Published: November 21, 2013
Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series.
Journal: Bioorganic & medicinal chemistry letters
Published: October 31, 2011
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Last Updated: 09/26/2026