Last Updated: 09/26/2026
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Found 25 publications
Considerations in Designing Clinical Trials of Novel Antibacterial Agents Using a Superiority Design.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Published: June 02, 2026
Randomized study of the efficacy, safety, and pharmacokinetics of SPR720 for the treatment of Mycobacterium avium complex pulmonary disease.
Journal: Scientific reports
Published: November 24, 2025
Serum Cell-Free DNA-based Detection of Mycobacterium avium Complex Infection.
Journal: American journal of respiratory and critical care medicine
Published: January 08, 2024
Impact of antibiotic pharmacokinetics in urine on recurrent bacteriuria following treatment of complicated urinary tract infections.
Journal: Antimicrobial agents and chemotherapy
Published: September 28, 2023
Population Pharmacokinetic Analyses for Tebipenem after Oral Administration of Pro-Drug Tebipenem Pivoxil Hydrobromide.
Journal: Antimicrobial agents and chemotherapy
Published: May 16, 2023
Evaluation of Factors Predictive of Efficacy Among Patients With Complicated Urinary Tract Infection and/or Acute Pyelonephritis.
Journal: Open forum infectious diseases
Published: March 08, 2023
Effect of tebipenem pivoxil hydrobromide on the normal gut microbiota of a healthy adult population in Sweden: a randomised controlled trial.
Journal: The Lancet. Microbe
Published: November 08, 2022
Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection.
Journal: The New England journal of medicine
Published: April 07, 2022
First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections.
Journal: Antimicrobial agents and chemotherapy
Published: September 07, 2021
Single- and Multiple-Ascending-Dose Study of the Safety, Tolerability, and Pharmacokinetics of the Polymyxin Derivative SPR206.
Journal: Antimicrobial agents and chemotherapy
Published: August 02, 2021
Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study of the Effects of Tebipenem Pivoxil Hydrobromide on QT/QTc Intervals in Healthy Subjects.
Journal: Antimicrobial agents and chemotherapy
Published: April 20, 2021
Safety, Pharmacokinetics, and Food Effect of Tebipenem Pivoxil Hydrobromide after Single and Multiple Ascending Oral Doses in Healthy Adult Subjects.
Journal: Antimicrobial agents and chemotherapy
Published: March 22, 2019
Last Updated: 09/26/2026