David A. Egan

Utrecht, UT 3584CH, Netherlands

Last Updated: 09/26/2026

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Found 26 publications

Bridging imaging-based in vitro methods from biomedical research to regulatory toxicology.

Bridging imaging-based in vitro methods from biomedical research to regulatory toxicology.

Journal: Archives of toxicology

Published: October 15, 2024

Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.

Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.

Journal: Frontiers in endocrinology

Published: April 22, 2022

Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.

Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.

Journal: Frontiers in pharmacology

Published: January 23, 2022

Identification of lysosome-targeting drugs with anti-inflammatory activity as potential invasion inhibitors of treatment resistant HER2 positive cancers.

Identification of lysosome-targeting drugs with anti-inflammatory activity as potential invasion inhibitors of treatment resistant HER2 positive cancers.

Journal: Cellular oncology (Dordrecht, Netherlands)

Published: March 10, 2021

High-Throughput Screening Identifies Idasanutlin as a Resensitizing Drug for Venetoclax-Resistant Neuroblastoma Cells.

High-Throughput Screening Identifies Idasanutlin as a Resensitizing Drug for Venetoclax-Resistant Neuroblastoma Cells.

Journal: Molecular cancer therapeutics

Published: August 05, 2020

Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening.

Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening.

Journal: SLAS discovery : advancing life sciences R & D

Published: May 14, 2020

Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia.

Epigenetic drug screen identifies the histone deacetylase inhibitor NSC3852 as a potential novel drug for the treatment of pediatric acute myeloid leukemia.

Journal: Pediatric blood & cancer

Published: October 08, 2018

TMEM59 potentiates Wnt signaling by promoting signalosome formation.

TMEM59 potentiates Wnt signaling by promoting signalosome formation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 11, 2018

DYRK1A Is a Regulator of S-Phase Entry in Hepatic Progenitor Cells.

DYRK1A Is a Regulator of S-Phase Entry in Hepatic Progenitor Cells.

Journal: Stem cells and development

Published: November 29, 2017

Improving Comprehension Efficiency of High Content Screening Data Through Interactive Visualizations.

Improving Comprehension Efficiency of High Content Screening Data Through Interactive Visualizations.

Journal: Assay and drug development technologies

Published: August 25, 2017

An Image-Based miRNA Screen Identifies miRNA-135s As Regulators of CNS Axon Growth and Regeneration by Targeting Krüppel-like Factor 4.

An Image-Based miRNA Screen Identifies miRNA-135s As Regulators of CNS Axon Growth and Regeneration by Targeting Krüppel-like Factor 4.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience

Published: March 09, 2017

Intra-tumour diversification in colorectal cancer at the single-cell level.

Intra-tumour diversification in colorectal cancer at the single-cell level.

Journal: Nature

Published: January 26, 2017

Showing 1-12 of 26

Last Updated: 09/26/2026