David A. Jacques
Botany Road
Sydney, NSW, Australia
Sydney, NSW, Australia
Last Updated: 09/26/2026
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Found 36 publications
Discovery of Potent 1,2,4-Triazole-Derived HIV Capsid Modulators with Dual-Stage Antiviral Activity via Targeting the Unexplored GTNQ Sub-Pocket Using a Multi-Site Binding Strategy.
Journal: Journal of medicinal chemistry
Published: April 02, 2026
Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: March 10, 2026
The intersection of viral mimicry and nuclear entry.
Journal: Trends in biochemical sciences
Published: April 17, 2025
Assessing the validity of leucine zipper constructs predicted by AlphaFold.
Journal: Protein science : a publication of the Protein Society
Published: October 14, 2024
The Human T-cell Leukemia Virus capsid protein is a potential drug target.
Journal: Nature communications
Published: September 18, 2024
Statement in Support of: "Virology under the Microscope-a Call for Rational Discourse".
Journal: mBio
Published: April 25, 2023
Statement in Support of: "Virology under the Microscope-a Call for Rational Discourse".
Journal: mSphere
Published: April 25, 2023
Statement in Support of: "Virology under the Microscope-a Call for Rational Discourse".
Journal: Journal of virology
Published: April 25, 2023
The HIV capsid mimics karyopherin engagement of FG-nucleoporins.
Journal: Nature
Published: March 23, 2023
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure.
Journal: eLife
Published: September 21, 2022
Evasion of cGAS and TRIM5 defines pandemic HIV.
Journal: Nature microbiology
Published: February 04, 2022
Last Updated: 09/26/2026