David C. Briggs
London, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 38 publications
Discovery of a sulfotyrosine-motif in the human TrkB extracellular domain required for agonist activation.
Journal: bioRxiv : the preprint server for biology
Published: June 04, 2026
A long-chain heparan sulfate capture mechanism directs paracrine GDNF-GFRα1 signalling through RET.
Journal: bioRxiv : the preprint server for biology
Published: June 04, 2026
Penetrant PKCβ mutation in ATLL displays a mixed gain-of-function.
Journal: The Biochemical journal
Published: August 12, 2025
Structural basis of Fanconi anemia pathway activation by FANCM.
Journal: The EMBO journal
Published: March 11, 2025
Unlocking the secrets of SARS-CoV-2 nsp3 by combining experiments with AlphaFold2 domain prediction.
Unlocking the secrets of SARS-CoV-2 nsp3 by combining experiments with AlphaFold2 domain prediction.
Journal: Life science alliance
Published: February 04, 2025
Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells.
Journal: bioRxiv : the preprint server for biology
Published: July 09, 2024
Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells.
Journal: Nature chemical biology
Published: June 28, 2024
Capture, mutual inhibition and release mechanism for aPKC-Par6 and its multisite polarity substrate Lgl.
Journal: Nature structural & molecular biology
Published: January 30, 2024
V3: an enigmatic isoform of the proteoglycan versican.
Journal: American journal of physiology. Cell physiology
Published: July 03, 2023
Molecular mechanism of decision-making in glycosaminoglycan biosynthesis.
Journal: Nature communications
Published: April 26, 2023
Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly.
Journal: Nature communications
Published: April 19, 2023
Last Updated: 09/26/2026