David C. Hornigold
Biopharmaceuticals R&D
Cambridge, ENG, United Kingdom
Cambridge, ENG, United Kingdom
Last Updated: 09/26/2026
Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 32 publications
P-Rex1 limits glucose clearance and suppresses hepatocyte glucose uptake and mitochondrial metabolism independently of its Rac-GEF activity.
Journal: Cell reports
Published: January 25, 2025
Roles for Prlhr/GPR10 and Npffr2/GPR74 in feeding responses to PrRP.
Journal: Molecular metabolism
Published: October 31, 2024
P-Rex2 suppresses glucose uptake into liver and skeletal muscle through different adaptor functions.
P-Rex2 suppresses glucose uptake into liver and skeletal muscle through different adaptor functions.
Journal: Scientific reports
Published: October 29, 2024
Establishing a Relationship between In Vitro Potency in Cell-Based Assays and Clinical Efficacious Concentrations for Approved GLP-1 Receptor Agonists.
Journal: Pharmaceutics
Published: August 19, 2024
The role of receptor activity-modifying proteins in obesity and diabetes mellitus.
Journal: Journal of molecular endocrinology
Published: June 07, 2024
Stimulating intestinal GIP release reduces food intake and body weight in mice.
Journal: Molecular metabolism
Published: February 14, 2024
P-Rex1 limits the agonist-induced internalization of GPCRs independently of its Rac-GEF activity.
Journal: Cell reports
Published: December 01, 2023
Targeting the PREX2/RAC1/PI3Kβ Signaling Axis Confers Sensitivity to Clinically Relevant Therapeutic Approaches in Melanoma.
Journal: Cancer research
Published: September 14, 2023
Self-assembled GLP-1/glucagon peptide nanofibrils prolong inhibition of food intake.
Journal: Frontiers in endocrinology
Published: May 04, 2023
Relaxin/insulin-like family peptide receptor 4 (Rxfp4) expressing hypothalamic neurons modulate food intake and preference in mice.
Journal: Molecular metabolism
Published: July 18, 2022
Last Updated: 09/26/2026