Last Updated: 09/26/2026
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Found 20 publications
A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.
Journal: Neuro-oncology
Published: March 25, 2017
Translational Pharmacokinetic-Pharmacodynamic Modeling and Simulation: Optimizing 5-Fluorouracil Dosing in Children With Pediatric Ependymoma.
Journal: CPT: pharmacometrics & systems pharmacology
Published: February 17, 2016
Simvastatin Hydroxy Acid Fails to Attain Sufficient Central Nervous System Tumor Exposure to Achieve a Cytotoxic Effect: Results of a Preclinical Cerebral Microdialysis Study.
Journal: Drug metabolism and disposition: the biological fate of chemicals
Published: November 25, 2015
Phase I study of 5-fluorouracil in children and young adults with recurrent ependymoma.
Journal: Neuro-oncology
Published: January 23, 2015
A phase I trial and PK study of cediranib (AZD2171), an orally bioavailable pan-VEGFR inhibitor, in children with recurrent or refractory primary CNS tumors.
Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Published: December 31, 2014
Mdm2 and aurora kinase a inhibitors synergize to block melanoma growth by driving apoptosis and immune clearance of tumor cells.
Journal: Cancer research
Published: November 16, 2014
An open-label, two-stage, phase II study of bevacizumab and lapatinib in children with recurrent or refractory ependymoma: a collaborative ependymoma research network study (CERN).
Journal: Journal of neuro-oncology
Published: October 22, 2014
Phase I dose escalation and pharmacokinetic study of oral gefitinib and irinotecan in children with refractory solid tumors.
Journal: Cancer chemotherapy and pharmacology
Published: June 09, 2014
Population pharmacokinetics of bevacizumab in children with osteosarcoma: implications for dosing.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: March 19, 2014
Determination of crizotinib in human and mouse plasma by liquid chromatography electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS).
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Published: February 07, 2014
Phase I and pharmacokinetic trial of PTC299 in pediatric patients with refractory or recurrent central nervous system tumors: a PBTC study.
Journal: Journal of neuro-oncology
Published: December 27, 2013
Last Updated: 09/26/2026