David Colecchia

Siena, Italy

Last Updated: 09/26/2026

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Found 19 publications

Targeted apoptotic immune modulator for the treatment of metastatic EGFR-positive solid tumors.

Targeted apoptotic immune modulator for the treatment of metastatic EGFR-positive solid tumors.

Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: May 29, 2025

Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy.

Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy.

Journal: Autophagy
Published: October 06, 2018

MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process.

MAPK15 is part of the ULK complex and controls its activity to regulate early phases of the autophagic process.

Journal: The Journal of biological chemistry
Published: April 24, 2018

Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B.

Alterations of autophagy in the peripheral neuropathy Charcot-Marie-Tooth type 2B.

Journal: Autophagy
Published: November 14, 2017

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.

Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.

Journal: Cell death & disease
Published: August 04, 2017

EGFR-Targeted Magnetic Nanovectors Recognize, in Vivo, Head and Neck Squamous Cells Carcinoma-Derived Tumors.

EGFR-Targeted Magnetic Nanovectors Recognize, in Vivo, Head and Neck Squamous Cells Carcinoma-Derived Tumors.

Journal: ACS medicinal chemistry letters
Published: July 10, 2017

Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.

Prodrugs of Pyrazolo[3,4-d]pyrimidines: From Library Synthesis to Evaluation as Potential Anticancer Agents in an Orthotopic Glioblastoma Model.

Journal: Journal of medicinal chemistry
Published: June 27, 2017

Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood-Brain Barrier.

Aptamer Functionalization of Nanosystems for Glioblastoma Targeting through the Blood-Brain Barrier.

Journal: Journal of medicinal chemistry
Published: May 05, 2017

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Journal: Autophagy
Published: January 23, 2016

Straightforward synthesis of a novel ring-fused pyrazole-lactam and in vitro cytotoxic activity on cancer cell lines.

Straightforward synthesis of a novel ring-fused pyrazole-lactam and in vitro cytotoxic activity on cancer cell lines.

Journal: European journal of medicinal chemistry
Published: October 21, 2015

Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery.

Improvement of pyrazolo[3,4-d]pyrimidines pharmacokinetic properties: nanosystem approaches for drug delivery.

Journal: Scientific reports
Published: October 07, 2015

MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation.

MAPK15 mediates BCR-ABL1-induced autophagy and regulates oncogene-dependent cell proliferation and tumor formation.

Journal: Autophagy
Published: August 21, 2015
Showing 1-12 of 19

Last Updated: 09/26/2026