David Fedida
2350 Health Sciences Mall, V6T 1Z3
Vancouver, BC, Canada
Vancouver, BC, Canada
Last Updated: 09/26/2026
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Found 60 publications
Graded activation of mutant K41C-KCNE1:KCNQ1 channel complexes by mefenamic acid.
Journal: Channels (Austin, Tex.)
Published: July 29, 2025
Electrophysiological characterization of the state-dependent inhibition of Kv7.1 and IKs by UCL2077.
Electrophysiological characterization of the state-dependent inhibition of Kv7.1 and IKs by UCL2077.
Journal: Molecular pharmacology
Published: June 26, 2025
The conductance of KCNQ2 and its pathogenic variants is determined by individual subunit gating.
Journal: Science advances
Published: March 05, 2025
A physiologically-relevant intermediate state structure of a voltage-gated potassium channel.
Journal: Nature communications
Published: January 17, 2025
Ion permeation through a narrow cavity constriction in KCNQ1 channels: Mechanism and implications for pathogenic variants.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: December 13, 2024
PUFA stabilizes a conductive state of the selectivity filter in IKs channels.
Journal: eLife
Published: October 31, 2024
Antiviral mechanisms and preclinical evaluation of amantadine analogs that continue to inhibit influenza A viruses with M2S31N-based drug resistance.
Journal: Antiviral research
Published: September 11, 2024
Voltage Clamp Fluorometry: Illuminating the Dynamics of Ion Channels.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: June 10, 2024
Dual effects of mefenamic acid on the IKs molecular complex.
Journal: British journal of pharmacology
Published: March 06, 2024
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes.
Journal: eLife
Published: September 14, 2023
Evaluating sequential and allosteric activation models in IKs channels with mutated voltage sensors.
Evaluating sequential and allosteric activation models in IKs channels with mutated voltage sensors.
Journal: The Journal of general physiology
Published: August 16, 2023
In Silico Evaluation of Hexamethylene Amiloride Derivatives as Potential Luminal Inhibitors of SARS-CoV-2 E Protein.
Journal: International journal of molecular sciences
Published: July 25, 2022
Last Updated: 09/26/2026