David House
Gunnels Wood Road
Stevenage, ENG, United Kingdom
Stevenage, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 23 publications
Proteome-Wide Target Identification Using Reactive Metallo-Scaffolds (r-mS): A Platform for Metallodrug Discovery.
Journal: Angewandte Chemie (International ed. in English)
Published: March 09, 2026
A Synergistic Inhibitor Development Strategy Against Human UDP-Galactose-4-Epimerase.
Journal: Angewandte Chemie (International ed. in English)
Published: September 15, 2025
Covalent fragment screening to inhibit the E3 ligase activity of bacterial NEL enzymes SspH1 and SspH2.
Journal: RSC chemical biology
Published: July 08, 2025
Conformational dynamics of the bacterial E3 ligase SspH1.
Journal: The Journal of biological chemistry
Published: June 13, 2025
Expedited SARS-CoV-2 Main Protease Inhibitor Discovery through Modular 'Direct-to-Biology' Screening.
Journal: Angewandte Chemie (International ed. in English)
Published: September 23, 2024
Enantioselective OTUD7B fragment discovery through chemoproteomics screening and high-throughput optimisation.
Journal: Communications chemistry
Published: August 30, 2024
Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics.
Journal: Nature communications
Published: July 26, 2024
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.
The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound.
Journal: Nature microbiology
Published: March 19, 2024
Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments.
Journal: ACS chemical biology
Published: April 21, 2023
Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome.
Journal: ACS chemical biology
Published: January 17, 2023
Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry.
Journal: RSC medicinal chemistry
Published: December 20, 2022
Publisher Correction: MOG analogues to explore the MCT2 pharmacophore, α-ketoglutarate biology and cellular effects of N-oxalylglycine.
Journal: Communications biology
Published: September 27, 2022
Last Updated: 09/26/2026