David J. Gallacher

Janssen R&D
Beerse, VLG, Belgium

Last Updated: 09/26/2026

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Found 59 publications

From surplus to scientific value: Repurposing vascular tissues for organ bath standardization to de-risk vasoactive liabilities.

From surplus to scientific value: Repurposing vascular tissues for organ bath standardization to de-risk vasoactive liabilities.

Journal: Journal of pharmacological and toxicological methods

Published: March 02, 2026

Risk of Revision and Patient-Reported Outcomes Following Primary UKR Performed Using Computer Navigation or Patient-Specific Instrumentation: An Analysis of National Joint Registry Data.

Risk of Revision and Patient-Reported Outcomes Following Primary UKR Performed Using Computer Navigation or Patient-Specific Instrumentation: An Analysis of National Joint Registry Data.

Journal: The Journal of bone and joint surgery. American volume

Published: June 19, 2025

The Effects of Computer Navigation and Patient-Specific Instrumentation on Risk of Revision, PROMs, and Mortality Following Primary TKR: An Analysis of National Joint Registry Data.

The Effects of Computer Navigation and Patient-Specific Instrumentation on Risk of Revision, PROMs, and Mortality Following Primary TKR: An Analysis of National Joint Registry Data.

Journal: The Journal of bone and joint surgery. American volume

Published: February 19, 2025

A Gaussian-plume based Monte Carlo method for calculating radiation dose in the near field of buildings.

A Gaussian-plume based Monte Carlo method for calculating radiation dose in the near field of buildings.

Journal: Journal of radiological protection : official journal of the Society for Radiological Protection

Published: November 10, 2023

Development of a new hazard scoring system in primary neuronal cell cultures for drug-induced acute neuronal toxicity identification in early drug discovery.

Development of a new hazard scoring system in primary neuronal cell cultures for drug-induced acute neuronal toxicity identification in early drug discovery.

Journal: Frontiers in pharmacology

Published: October 06, 2023

The Potential Mechanisms behind Loperamide-Induced Cardiac Arrhythmias Associated with Human Abuse and Extreme Overdose.

The Potential Mechanisms behind Loperamide-Induced Cardiac Arrhythmias Associated with Human Abuse and Extreme Overdose.

Journal: Biomolecules

Published: August 10, 2023

Evaluation of chronic drug-induced electrophysiological and cytotoxic effects using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs).

Evaluation of chronic drug-induced electrophysiological and cytotoxic effects using human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs).

Journal: Frontiers in pharmacology

Published: May 27, 2023

Does Enhanced Structural Maturity of hiPSC-Cardiomyocytes Better for the Detection of Drug-Induced Cardiotoxicity?

Does Enhanced Structural Maturity of hiPSC-Cardiomyocytes Better for the Detection of Drug-Induced Cardiotoxicity?

Journal: Biomolecules

Published: March 03, 2023

High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D Cultures.

High-Throughput Screening Assay for Detecting Drug-Induced Changes in Synchronized Neuronal Oscillations and Potential Seizure Risk Based on Ca2+ Fluorescence Measurements in Human Induced Pluripotent Stem Cell (hiPSC)-Derived Neuronal 2D and 3D Cultures.

Journal: Cells

Published: February 03, 2023

Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic doses.

Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic doses.

Journal: Regulatory toxicology and pharmacology : RTP

Published: August 01, 2022

Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?

Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?

Journal: European journal of pharmacology

Published: March 08, 2022

Identifying Acute Cardiac Hazard in Early Drug Discovery Using a Calcium Transient High-Throughput Assay in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Identifying Acute Cardiac Hazard in Early Drug Discovery Using a Calcium Transient High-Throughput Assay in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Journal: Frontiers in physiology

Published: December 17, 2021

Showing 1-12 of 59

Last Updated: 09/26/2026