David J. Picketts

Ottawa, ON, Canada

Last Updated: 09/26/2026

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Found 49 publications

ISWI remodeler facilitates cBAF genomic binding to drive cell fate transition.

ISWI remodeler facilitates cBAF genomic binding to drive cell fate transition.

Journal: bioRxiv : the preprint server for biology

Published: May 25, 2026

The ATRXt Protein Represses rDNA Transcription While Mirroring ATRX Interactions and Heterochromatin Localization.

The ATRXt Protein Represses rDNA Transcription While Mirroring ATRX Interactions and Heterochromatin Localization.

Journal: International journal of molecular sciences

Published: March 06, 2026

Pathogenic variants in the SMARCA1 gene cause a novel neurodevelopmental disorder.

Pathogenic variants in the SMARCA1 gene cause a novel neurodevelopmental disorder.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy

Published: February 03, 2026

The SMARCA5-DMRT1 Pioneer Complex Establishes Epigenetic Priming to Direct Male Germline Development.

The SMARCA5-DMRT1 Pioneer Complex Establishes Epigenetic Priming to Direct Male Germline Development.

Journal: Research square

Published: November 24, 2025

The SMARCA5-DMRT1 Pioneer Complex Establishes Epigenetic Priming to Direct Male Germline Development.

The SMARCA5-DMRT1 Pioneer Complex Establishes Epigenetic Priming to Direct Male Germline Development.

Journal: bioRxiv : the preprint server for biology

Published: August 21, 2025

Assigning Targetable Molecular Pathways to Transdiagnostic Subgroups Across Autism and Related Neurodevelopmental Disorders.

Assigning Targetable Molecular Pathways to Transdiagnostic Subgroups Across Autism and Related Neurodevelopmental Disorders.

Journal: bioRxiv : the preprint server for biology

Published: June 26, 2025

Interferon dependent immune memory during HSV-1 neuronal latency via increased H3K9me3 and restriction by ATRX.

Interferon dependent immune memory during HSV-1 neuronal latency via increased H3K9me3 and restriction by ATRX.

Journal: Nature communications

Published: January 29, 2025

The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis.

The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: January 14, 2025

It Takes a Village of Chromatin Remodelers to Regulate rDNA Expression.

It Takes a Village of Chromatin Remodelers to Regulate rDNA Expression.

Journal: International journal of molecular sciences

Published: December 30, 2024

SMARCA5 is required for the development of granule cell neuron precursors and Sonic Hedgehog Medulloblastoma growth.

SMARCA5 is required for the development of granule cell neuron precursors and Sonic Hedgehog Medulloblastoma growth.

Journal: Scientific reports

Published: September 16, 2024

Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms.

Single-cell profiling of brain pericyte heterogeneity following ischemic stroke unveils distinct pericyte subtype-targeted neural reprogramming potential and its underlying mechanisms.

Journal: Theranostics

Published: April 10, 2024

Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma.

Conditional Activation of c-MYC in Distinct Catecholaminergic Cells Drives Development of Neuroblastoma or Somatostatinoma.

Journal: Cancer research

Published: April 06, 2024

Showing 1-12 of 49

Last Updated: 09/26/2026