David L. Zechel

Kingston, ON, Canada

Last Updated: 09/26/2026

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Found 27 publications

Application of the YebF secretion pathway in Escherichia coli for rapid, on-plate screening of PETase libraries for improved activity.

Application of the YebF secretion pathway in Escherichia coli for rapid, on-plate screening of PETase libraries for improved activity.

Journal: RSC chemical biology

Published: March 11, 2026

Mining Thermophile Genomes for New PETases with Exceptional Thermostabilities Using Sequence Similarity Networks.

Mining Thermophile Genomes for New PETases with Exceptional Thermostabilities Using Sequence Similarity Networks.

Journal: Chembiochem : a European journal of chemical biology

Published: March 10, 2025

Analysis of the cryptic biosynthetic gene cluster encoding the RiPP curacozole reveals a phenylalanine-specific peptide hydroxylase.

Analysis of the cryptic biosynthetic gene cluster encoding the RiPP curacozole reveals a phenylalanine-specific peptide hydroxylase.

Journal: Chemical science

Published: April 05, 2024

The functional importance of bacterial oxidative phosphonate pathways.

The functional importance of bacterial oxidative phosphonate pathways.

Journal: Biochemical Society transactions

Published: December 02, 2022

Discovery of 3'-O-β-Glucosyltubercidin and the Nucleoside Specific Glycosyltransferase AvpGT through Genome Mining.

Discovery of 3'-O-β-Glucosyltubercidin and the Nucleoside Specific Glycosyltransferase AvpGT through Genome Mining.

Journal: ACS chemical biology

Published: November 10, 2022

Identification of Genes Essential for Sulfamate and Fluorine Incorporation During Nucleocidin Biosynthesis.

Identification of Genes Essential for Sulfamate and Fluorine Incorporation During Nucleocidin Biosynthesis.

Journal: Chembiochem : a European journal of chemical biology

Published: March 10, 2022

Biosynthesis of the Fungal Organophosphonate Fosfonochlorin Involves an Iron(II) and 2-(Oxo)glutarate Dependent Oxacyclase.

Biosynthesis of the Fungal Organophosphonate Fosfonochlorin Involves an Iron(II) and 2-(Oxo)glutarate Dependent Oxacyclase.

Journal: Chembiochem : a European journal of chemical biology

Published: July 16, 2021

Role of Two Exceptional trans Adenylation Domains and MbtH-like Proteins in the Biosynthesis of the Nonribosomal Peptide WS9324A from Streptomyces calvus ATCC 13382.

Role of Two Exceptional trans Adenylation Domains and MbtH-like Proteins in the Biosynthesis of the Nonribosomal Peptide WS9324A from Streptomyces calvus ATCC 13382.

Journal: Chembiochem : a European journal of chemical biology

Published: March 05, 2020

Secondary nucleotide messenger c-di-GMP exerts a global control on natural product biosynthesis in streptomycetes.

Secondary nucleotide messenger c-di-GMP exerts a global control on natural product biosynthesis in streptomycetes.

Journal: Nucleic acids research

Published: August 16, 2019

Rational Design of Hybrid Natural Products by Utilizing the Promiscuity of an Amide Synthetase.

Rational Design of Hybrid Natural Products by Utilizing the Promiscuity of an Amide Synthetase.

Journal: ACS chemical biology

Published: July 17, 2019

C-H Bond Cleavage Is Rate-Limiting for Oxidative C-P Bond Cleavage by the Mixed Valence Diiron-Dependent Oxygenase PhnZ.

C-H Bond Cleavage Is Rate-Limiting for Oxidative C-P Bond Cleavage by the Mixed Valence Diiron-Dependent Oxygenase PhnZ.

Journal: Biochemistry

Published: May 03, 2019

An Oxidative Pathway for Microbial Utilization of Methylphosphonic Acid as a Phosphate Source.

An Oxidative Pathway for Microbial Utilization of Methylphosphonic Acid as a Phosphate Source.

Journal: ACS chemical biology

Published: February 28, 2019

Showing 1-12 of 27

Last Updated: 09/26/2026