David Link-Reiner

Duesseldorf, NW, Germany

Last Updated: 09/26/2026

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Found 13 publications

Histamine H3 receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection.

Histamine H3 receptor antagonist/nitric oxide donors as novel promising therapeutic hybrid-tools for glaucoma and retinal neuroprotection.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: August 03, 2024

Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.

Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.

Journal: Journal of medicinal chemistry

Published: July 07, 2023

Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease.

Novel benzothiazole derivatives as multitargeted-directed ligands for the treatment of Alzheimer's disease.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: February 15, 2023

Benzophenone Derivatives with Histamine H3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.

Benzophenone Derivatives with Histamine H3 Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer's Disease.

Journal: Molecules (Basel, Switzerland)

Published: November 23, 2022

Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H3 and dopamine D3 receptors.

Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H3 and dopamine D3 receptors.

Journal: Bioorganic & medicinal chemistry

Published: October 07, 2022

Dual Targeting Ligands-Histamine H3 Receptor Ligands with Monoamine Oxidase B Inhibitory Activity-In Vitro and In Vivo Evaluation.

Dual Targeting Ligands-Histamine H3 Receptor Ligands with Monoamine Oxidase B Inhibitory Activity-In Vitro and In Vivo Evaluation.

Journal: Pharmaceutics

Published: September 12, 2022

OLHA (Nα-oleoylhistamine) modulates activity of mouse brain histaminergic neurons.

OLHA (Nα-oleoylhistamine) modulates activity of mouse brain histaminergic neurons.

Journal: Neuropharmacology

Published: January 28, 2022

Histamine H3 receptor antagonists with peptidomimetic (keto)piperazine structures to inhibit Aβ oligomerisation.

Histamine H3 receptor antagonists with peptidomimetic (keto)piperazine structures to inhibit Aβ oligomerisation.

Journal: Bioorganic & medicinal chemistry

Published: August 11, 2021

Biphenylalkoxyamine Derivatives-Histamine H3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity.

Biphenylalkoxyamine Derivatives-Histamine H3 Receptor Ligands with Butyrylcholinesterase Inhibitory Activity.

Journal: Molecules (Basel, Switzerland)

Published: May 19, 2021

Discovery of Potential, Dual-Active Histamine H3 Receptor Ligands with Combined Antioxidant Properties.

Discovery of Potential, Dual-Active Histamine H3 Receptor Ligands with Combined Antioxidant Properties.

Journal: Molecules (Basel, Switzerland)

Published: March 12, 2021

Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.

Cyanobiphenyls: Novel H3 receptor ligands with cholinesterase and MAO B inhibitory activity as multitarget compounds for potential treatment of Alzheimer's disease.

Journal: Bioorganic chemistry

Published: March 09, 2021

The Multi-Targeting Ligand ST-2223 with Histamine H3 Receptor and Dopamine D2/D3 Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors and Brain Oxidative Stress in Mice.

The Multi-Targeting Ligand ST-2223 with Histamine H3 Receptor and Dopamine D2/D3 Receptor Antagonist Properties Mitigates Autism-Like Repetitive Behaviors and Brain Oxidative Stress in Mice.

Journal: International journal of molecular sciences

Published: January 20, 2021

Showing 1-12 of 13

Last Updated: 09/26/2026