
Last Updated: 09/26/2026
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Found 92 publications
Orchestrated metal ion repositioning defines the dynamic catalytic strategy of the essential DNA repair nuclease APE1.
Journal: bioRxiv : the preprint server for biology
Published: May 25, 2026
Molecular damage associated with ageing drives inflammation in cardiovascular disease.
Journal: Nature reviews. Cardiology
Published: January 12, 2026
Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.
Journal: Research square
Published: December 03, 2025
Role of mitochondria in neuronal function and survival in the enteric and central nervous systems.
Journal: Cellular and molecular life sciences : CMLS
Published: October 29, 2025
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome.
Journal: Journal of medicinal chemistry
Published: September 03, 2025
In Pursuit of Best-in-Class MCL-1 Inhibitors: Discovery of Highly Potent 1,4-Indoyl Macrocycles with Favorable Physicochemical Properties.
Journal: Journal of medicinal chemistry
Published: August 18, 2025
Discovery and Optimization of Pyrazine Carboxamide AZ3246, a Selective HPK1 Inhibitor.
Journal: Journal of medicinal chemistry
Published: February 10, 2025
Molecular insights into the stimulation of SNM1A nuclease activity by CSB during interstrand crosslink processing.
Journal: bioRxiv : the preprint server for biology
Published: September 16, 2024
Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice.
Journal: Journal of biomedical science
Published: July 05, 2024
Introducing the Role of Genotoxicity in Neurodegenerative Diseases and Neuropsychiatric Disorders.
Journal: International journal of molecular sciences
Published: May 24, 2024
Targeting the Synthetic Lethal Relationship between FOCAD and TUT7 Represents a Potential Therapeutic Opportunity for TUT4/7 Small-Molecule Inhibitors in Cancer.
Journal: Molecular cancer therapeutics
Published: March 12, 2024
Last Updated: 09/26/2026