David Machalz
Berlin, BE, Germany
Last Updated: 09/26/2026
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Found 15 publications
Metabolism of the antipsychotic drug olanzapine by CYP3A43.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: May 18, 2022
A convenient test system for the identification of CYP4V2 inhibitors.
Journal: Molecular vision
Published: March 05, 2021
Structural insights into understudied human cytochrome P450 enzymes.
Journal: Drug discovery today
Published: January 14, 2021
Corticosteroid Biosynthesis Revisited: No Direct Hydroxylation of Pregnenolone by Steroid 21-Hydroxylase.
Journal: Frontiers in endocrinology
Published: November 26, 2020
Functional Expression of All Human Sulfotransferases in Fission Yeast, Assay Development, and Structural Models for Isoforms SULT4A1 and SULT6B1.
Journal: Biomolecules
Published: October 12, 2020
Discovery of a novel potent cytochrome P450 CYP4Z1 inhibitor.
Journal: European journal of medicinal chemistry
Published: September 28, 2020
A benzoxazole derivative as an inhibitor of anaerobic choline metabolism by human gut microbiota.
Journal: RSC medicinal chemistry
Published: June 20, 2020
New Proluciferin Substrates for Human CYP4 Family Enzymes.
Journal: Applied biochemistry and biotechnology
Published: March 03, 2020
Importance of asparagine-381 and arginine-487 for substrate recognition in CYP4Z1.
Journal: Biochemical pharmacology
Published: December 11, 2019
Fine-mapping of the substrate specificity of human steroid 21-hydroxylase (CYP21A2).
Journal: The Journal of steroid biochemistry and molecular biology
Published: July 11, 2019
Functional characterization and mechanistic modeling of the human cytochrome P450 enzyme CYP4A22.
Journal: FEBS letters
Published: April 07, 2019
Comparison of the three SARMs RAD-140, GLPG0492 and GSK-2881078 in two different in vitro bioassays, and in an in silico androgen receptor binding assay.
Journal: The Journal of steroid biochemistry and molecular biology
Published: November 14, 2018
Last Updated: 09/26/2026