David R. Da Rocha

Rio De Janeiro, RJ 24020141, Brazil

Last Updated: 09/26/2026

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Found 23 publications

Electrochemical and Theoretical Evaluation of Carbothioamide-Derived Corrosion Inhibitors for Mild Steel in Acidic Environments.

Electrochemical and Theoretical Evaluation of Carbothioamide-Derived Corrosion Inhibitors for Mild Steel in Acidic Environments.

Journal: Langmuir : the ACS journal of surfaces and colloids

Published: April 08, 2026

Molecular Hybridization of Naphthoquinones and Thiazoles: A Promising Strategy for Anticancer Drug Discovery.

Molecular Hybridization of Naphthoquinones and Thiazoles: A Promising Strategy for Anticancer Drug Discovery.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: November 07, 2025

PAV-05 Naphthoquinone Potently Inhibit Zika Virus Replication in Infected Cells.

PAV-05 Naphthoquinone Potently Inhibit Zika Virus Replication in Infected Cells.

Journal: Current topics in medicinal chemistry

Published: July 08, 2024

Naphthoquinones as a Promising Class of Compounds for Facing the Challenge of Parkinson's Disease.

Naphthoquinones as a Promising Class of Compounds for Facing the Challenge of Parkinson's Disease.

Journal: Pharmaceuticals (Basel, Switzerland)

Published: October 09, 2023

In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response.

In silico and pharmacological study of N,S-acetal juglone derivatives as inhibitors of the P2X7 receptor-promoted in vitro and in vivo inflammatory response.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: February 17, 2023

Synthesis, Biological Evaluation and Molecular Modeling Studies of Naphthoquinone Sulfonamides and Sulfonate Ester Derivatives as P2X7 Inhibitors.

Synthesis, Biological Evaluation and Molecular Modeling Studies of Naphthoquinone Sulfonamides and Sulfonate Ester Derivatives as P2X7 Inhibitors.

Journal: Molecules (Basel, Switzerland)

Published: November 23, 2022

Antitumoral effect of novel synthetic 8-hydroxy-2-((4-nitrophenyl)thio)naphthalene-1,4-dione (CNN16) via ROS-mediated DNA damage, apoptosis and anti-migratory effect in colon cancer cell line.

Antitumoral effect of novel synthetic 8-hydroxy-2-((4-nitrophenyl)thio)naphthalene-1,4-dione (CNN16) via ROS-mediated DNA damage, apoptosis and anti-migratory effect in colon cancer cell line.

Journal: Toxicology and applied pharmacology

Published: July 26, 2022

1,4-Naphthoquinone (CNN1) Induces Apoptosis through DNA Damage and Promotes Upregulation of H2AFX in Leukemia Multidrug Resistant Cell Line.

1,4-Naphthoquinone (CNN1) Induces Apoptosis through DNA Damage and Promotes Upregulation of H2AFX in Leukemia Multidrug Resistant Cell Line.

Journal: International journal of molecular sciences

Published: June 21, 2022

Juglone: A Versatile Natural Platform for Obtaining New Bioactive Compounds.

Juglone: A Versatile Natural Platform for Obtaining New Bioactive Compounds.

Journal: Current topics in medicinal chemistry

Published: March 29, 2021

Semisynthetic triterpenes led to the generation of selective antitrypanosomal lead compounds.

Semisynthetic triterpenes led to the generation of selective antitrypanosomal lead compounds.

Journal: Chemical biology & drug design

Published: December 25, 2020

Strategies for the Synthesis of Mono- and Bis-Thionaphthoquinones.

Strategies for the Synthesis of Mono- and Bis-Thionaphthoquinones.

Journal: Current organic synthesis

Published: October 27, 2020

Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against Trypanosoma cruzi.

Optimization of 1,4-Naphthoquinone Hit Compound: A Computational, Phenotypic, and In Vivo Screening against Trypanosoma cruzi.

Journal: Molecules (Basel, Switzerland)

Published: September 25, 2020

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Last Updated: 09/26/2026