David Schrama

Josef Schneider Str. 2
Wuerzburg, BY 97080, Germany

Last Updated: 09/26/2026

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Found 93 publications

MEK5/ERK5 inhibition sensitizes NRAS-mutant melanoma to MAPK-targeted therapy by preventing Cyclin D/CDK4-mediated G1/S progression.

MEK5/ERK5 inhibition sensitizes NRAS-mutant melanoma to MAPK-targeted therapy by preventing Cyclin D/CDK4-mediated G1/S progression.

Journal: Cell death & disease
Published: April 07, 2025

Optimization of Adcitmer, a Monomethyl-Auristatin E bearing antibody-drug conjugate for the treatment of CD56-expressing cancers.

Optimization of Adcitmer, a Monomethyl-Auristatin E bearing antibody-drug conjugate for the treatment of CD56-expressing cancers.

Journal: Journal for immunotherapy of cancer
Published: February 03, 2025

RB1 inactivation in cutaneous carcinomas.

RB1 inactivation in cutaneous carcinomas.

Journal: Histopathology
Published: August 06, 2024

Susceptibility of Melanoma Cells to Targeted Therapy Correlates with Protection by Blood Neutrophils.

Susceptibility of Melanoma Cells to Targeted Therapy Correlates with Protection by Blood Neutrophils.

Journal: Cancers
Published: April 08, 2024

Merkel Cell Carcinoma: Integrating Epidemiology, Immunology, and Therapeutic Updates.

Merkel Cell Carcinoma: Integrating Epidemiology, Immunology, and Therapeutic Updates.

Journal: American journal of clinical dermatology
Published: March 21, 2024

Current Progress in Vaccines against Merkel Cell Carcinoma: A Narrative Review and Update.

Current Progress in Vaccines against Merkel Cell Carcinoma: A Narrative Review and Update.

Journal: Vaccines
Published: March 19, 2024

Short- and long-term immunosuppressive effects of melanoma influence the prognostic value of the sentinel lymph node status.

Short- and long-term immunosuppressive effects of melanoma influence the prognostic value of the sentinel lymph node status.

Journal: European journal of cancer (Oxford, England : 1990)
Published: March 19, 2024

Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1.

Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1.

Journal: Journal of medical virology
Published: January 29, 2024

Loss of p14 diminishes immunogenicity in melanoma via non-canonical Wnt signaling by reducing the peptide surface density.

Loss of p14 diminishes immunogenicity in melanoma via non-canonical Wnt signaling by reducing the peptide surface density.

Journal: Molecular oncology
Published: January 03, 2024

Analyses of combined Merkel cell carcinomas with neuroblastic components suggests that loss of T antigen expression in Merkel cell carcinoma may result in cell cycle arrest and neuroblastic transdifferentiation.

Analyses of combined Merkel cell carcinomas with neuroblastic components suggests that loss of T antigen expression in Merkel cell carcinoma may result in cell cycle arrest and neuroblastic transdifferentiation.

Journal: The Journal of pathology
Published: January 02, 2024

Wnt/β-Catenin-Activated Nonpilomatrical Carcinoma of the Skin: A Case Series.

Wnt/β-Catenin-Activated Nonpilomatrical Carcinoma of the Skin: A Case Series.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Published: October 26, 2023

DNA Damage Stress Control Is a Truncated Large T Antigen and Euchromatic Histone Lysine Methyltransferase 2-Dependent Central Feature of Merkel Cell Carcinoma.

DNA Damage Stress Control Is a Truncated Large T Antigen and Euchromatic Histone Lysine Methyltransferase 2-Dependent Central Feature of Merkel Cell Carcinoma.

Journal: The Journal of investigative dermatology
Published: September 20, 2023
Showing 1-12 of 93

Last Updated: 09/26/2026