David Sumpton

Garscube Estate, Switchback Road
Glasgow, SCT, United Kingdom

Last Updated: 09/26/2026

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Found 69 publications

Publisher Correction: Colibactin-driven colon cancer requires adhesin-mediated epithelial binding.

Publisher Correction: Colibactin-driven colon cancer requires adhesin-mediated epithelial binding.

Journal: Nature
Published: February 07, 2026

Steroid-dependent metabolic rewiring reveals novel therapeutic and imaging approaches for glioblastoma.

Steroid-dependent metabolic rewiring reveals novel therapeutic and imaging approaches for glioblastoma.

Journal: Science advances
Published: January 23, 2026

The PP2A-B55α phosphatase is a master regulator of mitochondrial degradation and biogenesis.

The PP2A-B55α phosphatase is a master regulator of mitochondrial degradation and biogenesis.

Journal: Science advances
Published: October 03, 2025

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function.

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function.

Journal: Nature communications
Published: June 25, 2025

Increased mRNA translation delays tumour initiation and exposes a therapeutic vulnerability in lung cancer.

Increased mRNA translation delays tumour initiation and exposes a therapeutic vulnerability in lung cancer.

Journal: Molecular cancer
Published: May 30, 2025

ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.

ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity.

Journal: bioRxiv : the preprint server for biology
Published: April 01, 2025

SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis.

SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis.

Journal: Molecular cell
Published: March 31, 2025

A metabolism-specific drug-repurposing screen reveals itraconazole as a potent OXPHOS inhibitor in acute myeloid leukemia.

A metabolism-specific drug-repurposing screen reveals itraconazole as a potent OXPHOS inhibitor in acute myeloid leukemia.

Journal: Blood
Published: December 03, 2024

A metabolism-specific drug-repurposing screen reveals itraconazole as a potent OXPHOS inhibitor in acute myeloid leukemia.

A metabolism-specific drug-repurposing screen reveals itraconazole as a potent OXPHOS inhibitor in acute myeloid leukemia.

Journal: Blood
Published: December 03, 2024

Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer.

Functionally dominant hotspot mutations of mitochondrial ribosomal RNA genes in cancer.

Journal: Nature genetics
Published: November 08, 2024

Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ.

Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ.

Journal: Nature cell biology
Published: July 23, 2024

Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes.

Uridine phosphorylase-1 supports metastasis by altering immune and extracellular matrix landscapes.

Journal: EMBO reports
Published: July 02, 2024
Showing 1-12 of 69

Last Updated: 09/26/2026