Last Updated: 09/26/2026
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Found 83 publications
Direct binding of the C-terminal sequences of Bim and Bak contributes to efficient Bak activation.
Journal: Cell death and differentiation
Published: April 17, 2026
A high-resolution dimeric structure reveals a critical role of α-helix 9 in apoptotic Bax pore assembly in the mitochondrial membrane.
Journal: bioRxiv : the preprint server for biology
Published: January 09, 2026
Cancer-Associated BCL-2 Mutants Reveal Mechanisms Towards Venetoclax Resistance.
Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: December 09, 2025
Cancer-Associated BCL-2 Mutants Reveal Mechanisms Towards Venetoclax Resistance.
Journal: Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Published: December 09, 2025
VB-84922 is a small molecule that inhibits ER-to-golgi transport of SREBPs-SCAP complexes.
Journal: Frontiers in pharmacology
Published: October 25, 2025
High-content imaging of primary chronic lymphocytic leukemia cells predicts patient cohorts with distinct cellular drug responses.
Journal: iScience
Published: June 12, 2025
Small molecule protein assembly modulators with pan-cancer therapeutic efficacy.
Journal: Open biology
Published: December 17, 2024
Nesprin-2 contains BH3-like motifs that can promote cell death.
Journal: Cell death discovery
Published: November 15, 2024
CISD2 counteracts the inhibition of ER-mitochondrial calcium transfer by anti-apoptotic BCL-2.
Journal: Biochimica et biophysica acta. Molecular cell research
Published: May 09, 2024
Sterol-like drugs potentiate statin-triggered prostate cancer cell death by inhibiting SREBP2 nuclear translocation.
Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Published: February 26, 2024
The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death.
Journal: The Biochemical journal
Published: February 05, 2024
Live Cell Painting: New nontoxic dye to probe cell physiology in high content screening.
Journal: SLAS discovery : advancing life sciences R & D
Published: September 15, 2023
Last Updated: 09/26/2026