Dean C. Pask

Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 10 publications

Maintenance of hematopoietic stem cells by tyrosine-unphosphorylated STAT5 and JAK inhibition.

Maintenance of hematopoietic stem cells by tyrosine-unphosphorylated STAT5 and JAK inhibition.

Journal: Blood advances
Published: June 20, 2024

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis.

Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis.

Journal: Nature
Published: March 19, 2024

STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion.

STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion.

Journal: Blood
Published: September 07, 2021

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.

Journal: Blood
Published: December 11, 2017

Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage.

Mutant calreticulin knockin mice develop thrombocytosis and myelofibrosis without a stem cell self-renewal advantage.

Journal: Blood
Published: September 12, 2017

Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.

Corrigendum: Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.

Journal: Nature communications
Published: July 29, 2017

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment.

Journal: Cell reports
Published: October 15, 2016

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming.

Journal: Nature communications
Published: June 23, 2015

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease.

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease.

Journal: Blood
Published: April 03, 2014

Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion.

Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion.

Journal: PLoS biology
Published: December 15, 2012
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Last Updated: 09/26/2026