Dean Paes
Maastricht, LI, Netherlands
Last Updated: 09/26/2026
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Found 17 publications
Beta-amyloid interacts with and activates the long-form phosphodiesterase PDE4D5 in neuronal cells to reduce cAMP availability.
Journal: FEBS letters
Published: January 16, 2024
A review on the safety of growth factors commonly used in cultivated meat production.
Journal: Comprehensive reviews in food science and food safety
Published: October 31, 2023
Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis.
Journal: Brain, behavior, and immunity
Published: September 14, 2022
Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-β pathology.
Journal: Cellular and molecular life sciences : CMLS
Published: July 04, 2022
Soluble guanylate cyclase stimulator riociguat improves spatial memory in mice via peripheral mechanisms.
Journal: Neuroscience letters
Published: January 04, 2022
Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types.
Journal: Biophysical journal
Published: December 23, 2021
Biased 5-HT1A receptor agonists F13714 and NLX-101 differentially affect pattern separation and neuronal plasticity in rats after acute and chronic treatment.
Journal: Molecular and cellular neurosciences
Published: October 07, 2021
The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors.
Journal: Pharmacological reviews
Published: July 08, 2021
PDE inhibition in distinct cell types to reclaim the balance of synaptic plasticity.
Journal: Theranostics
Published: July 15, 2020
Pharmacological inhibition of phosphodiesterase 7 enhances consolidation processes of spatial memory.
Journal: Neurobiology of learning and memory
Published: June 30, 2020
Inhibition of PDE2 and PDE4 synergistically improves memory consolidation processes.
Journal: Neuropharmacology
Published: April 24, 2020
Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer's disease.
Journal: Neurobiology of aging
Published: April 09, 2020
Last Updated: 09/26/2026