Deborah Grifagni

Sesto Fiorentino, Italy

Last Updated: 09/26/2026

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Found 15 publications

Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self-Sufficient Viral Restriction Factors.

Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self-Sufficient Viral Restriction Factors.

Journal: Angewandte Chemie (International ed. in English)

Published: December 09, 2025

A novel mutation in FDX2 provides insights into the pathogenesis of MEOAL mitochondrial neuromuscular disease.

A novel mutation in FDX2 provides insights into the pathogenesis of MEOAL mitochondrial neuromuscular disease.

Journal: Cell death & disease

Published: July 22, 2025

Shedding Light on the Electron Delocalization Pathway at the [Fe2S2]2+ Cluster of FDX2.

Shedding Light on the Electron Delocalization Pathway at the [Fe2S2]2+ Cluster of FDX2.

Journal: Inorganic chemistry

Published: March 23, 2025

A Structural Investigation of the Interaction between a GC-376-Based Peptidomimetic PROTAC and Its Precursor with the Viral Main Protease of Coxsackievirus B3.

A Structural Investigation of the Interaction between a GC-376-Based Peptidomimetic PROTAC and Its Precursor with the Viral Main Protease of Coxsackievirus B3.

Journal: Biomolecules

Published: July 16, 2024

Unraveling the molecular determinants of a rare human mitochondrial disorder caused by the P144L mutation of FDX2.

Unraveling the molecular determinants of a rare human mitochondrial disorder caused by the P144L mutation of FDX2.

Journal: Protein science : a publication of the Protein Society

Published: June 10, 2024

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Journal: ACS chemical biology

Published: January 17, 2024

Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2.

Development of a GC-376 Based Peptidomimetic PROTAC as a Degrader of 3-Chymotrypsin-like Protease of SARS-CoV-2.

Journal: ACS medicinal chemistry letters

Published: October 31, 2023

Biochemical and cellular characterization of the CISD3 protein: Molecular bases of cluster release and destabilizing effects of nitric oxide.

Biochemical and cellular characterization of the CISD3 protein: Molecular bases of cluster release and destabilizing effects of nitric oxide.

Journal: The Journal of biological chemistry

Published: October 24, 2023

The hope and hype of ellagic acid and urolithins as ligands of SARS-CoV-2 Nsp5 and inhibitors of viral replication.

The hope and hype of ellagic acid and urolithins as ligands of SARS-CoV-2 Nsp5 and inhibitors of viral replication.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: August 28, 2023

Paramagnetic NMR to study iron sulfur proteins: 13C detected experiments illuminate the vicinity of the metal center.

Paramagnetic NMR to study iron sulfur proteins: 13C detected experiments illuminate the vicinity of the metal center.

Journal: Journal of biomolecular NMR

Published: May 31, 2023

Gold-Based Metal Drugs as Inhibitors of Coronavirus Proteins: The Inhibition of SARS-CoV-2 Main Protease by Auranofin and Its Analogs.

Gold-Based Metal Drugs as Inhibitors of Coronavirus Proteins: The Inhibition of SARS-CoV-2 Main Protease by Auranofin and Its Analogs.

Journal: Biomolecules

Published: October 03, 2022

1H, 13C and 15N assignment of the human mitochondrial paramagnetic iron-sulfur protein CISD3.

1H, 13C and 15N assignment of the human mitochondrial paramagnetic iron-sulfur protein CISD3.

Journal: Biomolecular NMR assignments

Published: September 13, 2022

Showing 1-12 of 15

Last Updated: 09/26/2026