Deborah Hirt - Publications

Pharmacokinetic modeling to support WHO-weight band dosing of a new pediatric darunavir/ritonavir (120/20 mg) fixed-dose combination tablet for children at least 3 years old and weighing 10 to less than 35 kg.

Journal: Journal of acquired immune deficiency syndromes (1999)

Published: August 21, 2026

Piperacillin Population Pharmacokinetics in Children Supported With Extracorporeal Membrane Oxygenation.

Journal: Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

Published: August 06, 2026

Cefazolin population pharmacokinetics in children undergoing maintenance hemodialysis for kidney failure.

Journal: Antimicrobial agents and chemotherapy

Published: October 02, 2025

Pharmacokinetics of cefotaxime and its metabolite desacetyl-cefotaxime to optimize dosing in critically ill children and children with sickle cell disease.

Journal: The Journal of antimicrobial chemotherapy

Published: August 01, 2025

Assessment of the steady-state drug-drug interactions between dolutegravir and ritonavir-boosted darunavir in adolescents.

Journal: AIDS (London, England)

Published: January 27, 2025

Improving cefazolin exposure in critically ill children using a population pharmacokinetic model.

Journal: British journal of clinical pharmacology

Published: April 24, 2024

A rapid LC-MS/MS method for the simultaneous quantification of ivacaftor, lumacaftor, elexacaftor, tezacaftor, hexyl-methyl ivacaftor and ivacaftor carboxylate in human plasma.

Journal: Journal of pharmaceutical and biomedical analysis

Published: April 12, 2024

Simultaneous pharmacokinetic modeling of unbound and total darunavir with ritonavir in adolescents: a substudy of the SMILE trial.

Journal: Antimicrobial agents and chemotherapy

Published: December 13, 2023

Optimization of vigabatrin dosage in children with epileptic spasms: A population pharmacokinetic approach.

Journal: British journal of clinical pharmacology

Published: August 30, 2023

Correction to: Beta-lactam exposure and safety in intermittent or continuous infusion in critically ill children: an observational monocenter study.

Journal: European journal of pediatrics

Published: December 18, 2022

Population pharmacokinetics of unbound and total dolutegravir concentrations in children aged 12 years and older: a PK substudy of the SMILE trial.

Journal: The Journal of antimicrobial chemotherapy

Published: October 15, 2022

Pharmacokinetic profile of acyclovir in a child receiving continuous kidney replacement therapy for acute liver failure.

Journal: Pediatric nephrology (Berlin, Germany)

Published: August 17, 2022