Denis P. Harkin

Craigavon, NIR, United Kingdom

Last Updated: 09/26/2026

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Found 33 publications

Immune microenvironment modulation following neoadjuvant therapy for oesophageal adenocarcinoma: a translational analysis of the DEBIOC clinical trial.

Immune microenvironment modulation following neoadjuvant therapy for oesophageal adenocarcinoma: a translational analysis of the DEBIOC clinical trial.

Journal: ESMO open

Published: May 23, 2024

Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification.

Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research

Published: February 02, 2022

Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors.

Cancer-Associated SF3B1 Mutations Confer a BRCA-Like Cellular Phenotype and Synthetic Lethality to PARP Inhibitors.

Journal: Cancer research

Published: June 08, 2021

Validation of the DNA Damage Immune Response Signature in Patients With Triple-Negative Breast Cancer From the SWOG 9313c Trial.

Validation of the DNA Damage Immune Response Signature in Patients With Triple-Negative Breast Cancer From the SWOG 9313c Trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Published: October 29, 2019

Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastrozole versus tamoxifen and acceptability of treatment.

Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastrozole versus tamoxifen and acceptability of treatment.

Journal: BMJ open

Published: December 24, 2018

High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum.

High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum.

Journal: Cancer

Published: October 23, 2018

Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma.

Immune activation by DNA damage predicts response to chemotherapy and survival in oesophageal adenocarcinoma.

Journal: Gut

Published: September 19, 2018

Analytical validation of a prognostic prostate cancer gene expression assay using formalin fixed paraffin embedded tissue.

Analytical validation of a prognostic prostate cancer gene expression assay using formalin fixed paraffin embedded tissue.

Journal: BMC medical genomics

Published: April 04, 2018

Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy.

Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology

Published: October 19, 2017

Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer.

Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer.

Journal: Laboratory investigation; a journal of technical methods and pathology

Published: June 04, 2017

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export.

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export.

Journal: Nucleic acids research

Published: March 16, 2017

Reply to L. Casadaban et al.

Reply to L. Casadaban et al.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Published: January 24, 2017

Showing 1-12 of 33

Last Updated: 09/26/2026