Denise Klatt

Hannover, NI 30625, Germany

Last Updated: 09/26/2026

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Found 20 publications

Optimized lentivirus-derived virus-like particles for efficient delivery of Cas9-based genome editors.

Optimized lentivirus-derived virus-like particles for efficient delivery of Cas9-based genome editors.

Journal: Nucleic acids research
Published: February 17, 2026

Transduction of Quiescent Human Hematopoietic Stem and Progenitor Cells Using Lentiviral Vectors and Virus-Like Particles.

Transduction of Quiescent Human Hematopoietic Stem and Progenitor Cells Using Lentiviral Vectors and Virus-Like Particles.

Journal: Current protocols
Published: January 27, 2026

Have we really solved rAAV6 toxicity? A closer look at mannose-coupled rAAV6 vectors.

Have we really solved rAAV6 toxicity? A closer look at mannose-coupled rAAV6 vectors.

Journal: Molecular therapy. Nucleic acids
Published: July 03, 2025

Modeling integration site data for safety assessment with MELISSA.

Modeling integration site data for safety assessment with MELISSA.

Journal: Nature communications
Published: October 02, 2024

UM171 enhances fitness and engraftment of gene-modified hematopoietic stem cells from patients with sickle cell disease.

UM171 enhances fitness and engraftment of gene-modified hematopoietic stem cells from patients with sickle cell disease.

Journal: Blood advances
Published: June 11, 2024

Engineered packaging cell line for the enhanced production of baboon-enveloped retroviral vectors.

Engineered packaging cell line for the enhanced production of baboon-enveloped retroviral vectors.

Journal: Molecular therapy. Nucleic acids
Published: May 29, 2024

Swapping the serotype: A novel helper-dependent adenoviral vector platform for in vivo HSC gene therapy.

Swapping the serotype: A novel helper-dependent adenoviral vector platform for in vivo HSC gene therapy.

Journal: Molecular therapy. Methods & clinical development
Published: June 19, 2023

Epitope editing enables targeted immunotherapy of acute myeloid leukaemia.

Epitope editing enables targeted immunotherapy of acute myeloid leukaemia.

Journal: Nature
Published: September 17, 2022

A Multiplex CRISPR-Screen Identifies PLA2G4A as Prognostic Marker and Druggable Target for HOXA9 and MEIS1 Dependent AML.

A Multiplex CRISPR-Screen Identifies PLA2G4A as Prognostic Marker and Druggable Target for HOXA9 and MEIS1 Dependent AML.

Journal: International journal of molecular sciences
Published: May 24, 2021

Efficient Genetic Safety Switches for Future Application of iPSC-Derived Cell Transplants.

Efficient Genetic Safety Switches for Future Application of iPSC-Derived Cell Transplants.

Journal: Journal of personalized medicine
Published: May 07, 2021

Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis.

Airway basal cells show a dedifferentiated KRT17highPhenotype and promote fibrosis in idiopathic pulmonary fibrosis.

Journal: Nature communications
Published: October 06, 2020

Competitive sgRNA Screen Identifies p38 MAPK as a Druggable Target to Improve HSPC Engraftment.

Competitive sgRNA Screen Identifies p38 MAPK as a Druggable Target to Improve HSPC Engraftment.

Journal: Cells
Published: August 18, 2020
Showing 1-12 of 20

Last Updated: 09/26/2026