Dennis J. Selkoe

Dennis J. Selkoe

Neurology
60 Fenwood Road
1st Floor Hale Building For Transformative Medicine
Boston, MA 02115

Last Updated: 09/26/2026

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Found 189 publications

Aβ Aggregates Bind the U1 Spliceosomal Ribonucleoprotein in Alzheimer Disease Brain.

Aβ Aggregates Bind the U1 Spliceosomal Ribonucleoprotein in Alzheimer Disease Brain.

Journal: bioRxiv : the preprint server for biology
Published: June 12, 2026

Health phenome of Parkinson's patients reveals prominent mood-sleep cluster.

Health phenome of Parkinson's patients reveals prominent mood-sleep cluster.

Journal: Parkinsonism & related disorders
Published: June 02, 2026

Recent Cochrane review has serious flaws: A perspective of clinicians and researchers from around the world.

Recent Cochrane review has serious flaws: A perspective of clinicians and researchers from around the world.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: May 13, 2026

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media.

Novel Monoclonal Antibody Detects Small Aβ Oligomers More Sensitively Than Lecanemab in Alzheimer's Disease CSF, Serum and Culture Media.

Journal: Annals of neurology
Published: December 18, 2025

Immunotherapy with B28, an antibody to Aβ oligomers, potently decreases amyloid plaques, microgliosis, and memory decline in APP knock-in mice.

Immunotherapy with B28, an antibody to Aβ oligomers, potently decreases amyloid plaques, microgliosis, and memory decline in APP knock-in mice.

Journal: Cell reports
Published: December 11, 2025

Higher-molecular-weight a-synuclein oligomers are increased in the brain cytosol of patients with dementia with Lewy bodies.

Higher-molecular-weight a-synuclein oligomers are increased in the brain cytosol of patients with dementia with Lewy bodies.

Journal: NPJ Parkinson's disease
Published: October 26, 2025

Baseline and placebo-related imaging, cerebrospinal fluid, plasma biomarker, and cognitive findings in unimpaired PSEN1 E280A mutation carriers and non-carriers in the Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Colombia Trial.

Baseline and placebo-related imaging, cerebrospinal fluid, plasma biomarker, and cognitive findings in unimpaired PSEN1 E280A mutation carriers and non-carriers in the Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Colombia Trial.

Journal: EBioMedicine
Published: October 10, 2025

CNS-Tau Specific Antibodies Illuminate Disease Signatures Across Tauopathies.

CNS-Tau Specific Antibodies Illuminate Disease Signatures Across Tauopathies.

Journal: bioRxiv : the preprint server for biology
Published: September 26, 2025

Nasal administration of Protollin enhances monocyte phagocytosis and decreases CD8+ T cell cytotoxicity in subjects with early Alzheimer's disease: a Phase 1 clinical trial.

Nasal administration of Protollin enhances monocyte phagocytosis and decreases CD8+ T cell cytotoxicity in subjects with early Alzheimer's disease: a Phase 1 clinical trial.

Journal: npj aging
Published: September 18, 2025

Parkinson disease is a fatty acidopathy.

Parkinson disease is a fatty acidopathy.

Journal: Nature reviews. Neurology
Published: September 02, 2025

Target product profiles for treatments to delay or prevent symptomatic Alzheimer's disease.

Target product profiles for treatments to delay or prevent symptomatic Alzheimer's disease.

Journal: Nature medicine
Published: August 26, 2025

Plasma levels of an N-terminal tau fragment predict Alzheimer's and neurodegenerative disease biomarkers in autosomal dominant Alzheimer's disease.

Plasma levels of an N-terminal tau fragment predict Alzheimer's and neurodegenerative disease biomarkers in autosomal dominant Alzheimer's disease.

Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: August 14, 2025
Showing 1-12 of 189

Last Updated: 09/26/2026