Derek J. Platt

Internal Medicine
4590 Nash Way
Saint Louis, MO 63110

Last Updated: 09/26/2026

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Found 15 publications

Regulation of cGAS and STING signaling during inflammation and infection.

Regulation of cGAS and STING signaling during inflammation and infection.

Journal: The Journal of biological chemistry
Published: October 04, 2021

Transferrable protection by gut microbes against STING-associated lung disease.

Transferrable protection by gut microbes against STING-associated lung disease.

Journal: Cell reports
Published: October 10, 2020

Immunopathology of Zika virus infection.

Immunopathology of Zika virus infection.

Journal: Advances in virus research
Published: July 27, 2020

HSV-1 and Zika Virus but Not SARS-CoV-2 Replicate in the Human Cornea and Are Restricted by Corneal Type III Interferon.

HSV-1 and Zika Virus but Not SARS-CoV-2 Replicate in the Human Cornea and Are Restricted by Corneal Type III Interferon.

Journal: Cell reports
Published: December 13, 2019

STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice.

STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice.

Journal: Cell reports
Published: August 21, 2019

A Human STAT1 Gain-of-Function Mutation Impairs CD8+ T Cell Responses against Gammaherpesvirus 68.

A Human STAT1 Gain-of-Function Mutation Impairs CD8+ T Cell Responses against Gammaherpesvirus 68.

Journal: Journal of virology
Published: February 20, 2019

A Human Gain-of-Function STING Mutation Causes Immunodeficiency and Gammaherpesvirus-Induced Pulmonary Fibrosis in Mice.

A Human Gain-of-Function STING Mutation Causes Immunodeficiency and Gammaherpesvirus-Induced Pulmonary Fibrosis in Mice.

Journal: Journal of virology
Published: October 10, 2018

STING-associated lung disease in mice relies on T cells but not type I interferon.

STING-associated lung disease in mice relies on T cells but not type I interferon.

Journal: The Journal of allergy and clinical immunology
Published: August 24, 2018

Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice.

Zika virus-related neurotropic flaviviruses infect human placental explants and cause fetal demise in mice.

Journal: Science translational medicine
Published: August 17, 2017

Consequences of congenital Zika virus infection.

Consequences of congenital Zika virus infection.

Journal: Current opinion in virology
Published: August 15, 2017

STING-associated vasculopathy develops independently of IRF3 in mice.

STING-associated vasculopathy develops independently of IRF3 in mice.

Journal: The Journal of experimental medicine
Published: July 28, 2017

Zika virus infection damages the testes in mice.

Zika virus infection damages the testes in mice.

Journal: Nature
Published: September 23, 2016
Showing 1-12 of 15

Last Updated: 09/26/2026