Di Kang

Jiangsu Key Laboratory For Functional Substance Of Chinese Medicine
Nanjing, China

Last Updated: 09/26/2026

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Found 10 publications

Recent developments in overcoming FLT3 inhibitor resistance.

Recent developments in overcoming FLT3 inhibitor resistance.

Journal: Future medicinal chemistry

Published: January 22, 2026

Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors.

Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors.

Journal: Journal of medicinal chemistry

Published: April 24, 2024

Effect of Celastrol Based on IRAK4/ERK/p38 Signaling Pathway on Proliferation and Apoptosis of Multiple Myeloma Cells

Effect of Celastrol Based on IRAK4/ERK/p38 Signaling Pathway on Proliferation and Apoptosis of Multiple Myeloma Cells

Journal: Zhongguo shi yan xue ye xue za zhi

Published: February 06, 2022

Triptolide Shows High Sensitivity and Low Toxicity Against Acute Myeloid Leukemia Cell Lines Through Inhibiting WSTF-RNAPII Complex.

Triptolide Shows High Sensitivity and Low Toxicity Against Acute Myeloid Leukemia Cell Lines Through Inhibiting WSTF-RNAPII Complex.

Journal: Frontiers in oncology

Published: November 09, 2021

Discovery of a Potent and Selective FLT3 Inhibitor (Z)-N-(5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-4-methyl-1H-pyrrol-3-yl)-3-(pyrrolidin-1-yl)propanamide with Improved Drug-like Properties and Superior Efficacy in FLT3-ITD-Positive Acute Myeloid Leukemia.

Discovery of a Potent and Selective FLT3 Inhibitor (Z)-N-(5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-4-methyl-1H-pyrrol-3-yl)-3-(pyrrolidin-1-yl)propanamide with Improved Drug-like Properties and Superior Efficacy in FLT3-ITD-Positive Acute Myeloid Leukemia.

Journal: Journal of medicinal chemistry

Published: April 02, 2021

The InR/Akt/TORC1 Growth-Promoting Signaling Negatively Regulates JAK/STAT Activity and Migratory Cell Fate during Morphogenesis.

The InR/Akt/TORC1 Growth-Promoting Signaling Negatively Regulates JAK/STAT Activity and Migratory Cell Fate during Morphogenesis.

Journal: Developmental cell

Published: February 15, 2017

Dlg5 maintains apical polarity by promoting membrane localization of Crumbs during Drosophila oogenesis.

Dlg5 maintains apical polarity by promoting membrane localization of Crumbs during Drosophila oogenesis.

Journal: Scientific reports

Published: March 31, 2016

Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography.

Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography.

Journal: Journal of medicinal chemistry

Published: December 04, 2015

In vivo RNAi screen identifies candidate signaling genes required for collective cell migration in Drosophila ovary.

In vivo RNAi screen identifies candidate signaling genes required for collective cell migration in Drosophila ovary.

Journal: Science China. Life sciences

Published: July 09, 2014

Identification of Novel Selective Lysine-Specific Demethylase 1 (LSD1) Inhibitors Using a Pharmacophore-Based Virtual Screening Combined with Docking.

Identification of Novel Selective Lysine-Specific Demethylase 1 (LSD1) Inhibitors Using a Pharmacophore-Based Virtual Screening Combined with Docking.

Journal: Chemical biology & drug design

Published: June 23, 2014

Showing 1-10 of 10

Last Updated: 09/26/2026