Diane V. Lefley
Beech Hill Road
Sheffield, ENG, United Kingdom
Sheffield, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 16 publications
Mouse Models of Breast Cancer Bone Metastasis.
Journal: Methods in molecular biology (Clifton, N.J.)
Published: May 31, 2025
ATM inhibition increases the anti-tumor efficacy of radium-223 (Ra-223) against prostate cancer bone metastasis in preclinical models.
Journal: JBMR plus
Published: March 11, 2025
Losartan alters osteoblast differentiation and increases bone mass through inhibition of TGFB signalling in vitro and in an OIM mouse model.
Journal: Bone reports
Published: February 22, 2024
Novel Methods of Targeting IL-1 Signalling for the Treatment of Breast Cancer Bone Metastasis.
Journal: Cancers
Published: August 29, 2022
Oestradiol Contributes to Differential Antitumour Effects of Adjuvant Zoledronic Acid Observed Between Pre- and Post-Menopausal Women.
Journal: Frontiers in endocrinology
Published: July 29, 2021
IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer.
Journal: NPJ breast cancer
Published: October 23, 2020
Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts.
Journal: Breast cancer research : BCR
Published: July 11, 2019
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling.
Journal: Nature communications
Published: February 26, 2019
Pharmacological inhibition of the IKKε/TBK-1 axis potentiates the anti-tumour and anti-metastatic effects of Docetaxel in mouse models of breast cancer.
Journal: Cancer letters
Published: November 21, 2018
Endogenous Production of IL1B by Breast Cancer Cells Drives Metastasis and Colonization of the Bone Microenvironment.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research
Published: July 11, 2018
Erratum to: Loss of plakoglobin promotes cell-cell contact, increased invasion and breast cancer cell dissemination in vivo.
Journal: Breast cancer research : BCR
Published: March 06, 2017
IL-1 drives breast cancer growth and bone metastasis in vivo.
Journal: Oncotarget
Published: June 01, 2016
Last Updated: 09/26/2026