Didier Negre

Lyon, 69007, France

Last Updated: 09/26/2026

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Found 13 publications

A Synthetic Circuit Empowering Reprogrammed B Cells for Therapeutic Proteins Expression Regulated by Tumor Detection.

A Synthetic Circuit Empowering Reprogrammed B Cells for Therapeutic Proteins Expression Regulated by Tumor Detection.

Journal: Journal of immunotherapy (Hagerstown, Md. : 1997)
Published: February 01, 2024

Engineering B cells with customized therapeutic responses using a synthetic circuit.

Engineering B cells with customized therapeutic responses using a synthetic circuit.

Journal: Molecular therapy. Nucleic acids
Published: January 13, 2023

Knockdown of regulatory associated protein of TOR (raptor) in hypothalamus-stimulated folliculogenesis and induced ovarian cysts.

Knockdown of regulatory associated protein of TOR (raptor) in hypothalamus-stimulated folliculogenesis and induced ovarian cysts.

Journal: Reproduction, fertility, and development
Published: February 26, 2022

Efficient adoptive transfer of autologous modified B cells: a new humanized platform mouse model for testing B cells reprogramming therapies.

Efficient adoptive transfer of autologous modified B cells: a new humanized platform mouse model for testing B cells reprogramming therapies.

Journal: Cancer immunology, immunotherapy : CII
Published: June 01, 2021

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency.

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiency.

Journal: Blood advances
Published: October 23, 2018

Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent.

Measles virus envelope pseudotyped lentiviral vectors transduce quiescent human HSCs at an efficiency without precedent.

Journal: Blood advances
Published: April 18, 2017

Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.

Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.

Journal: Journal of thrombosis and haemostasis : JTH
Published: October 28, 2015

Heparan sulfate-dependent enhancement of henipavirus infection.

Heparan sulfate-dependent enhancement of henipavirus infection.

Journal: mBio
Published: March 12, 2015

Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs.

Baboon envelope pseudotyped LVs outperform VSV-G-LVs for gene transfer into early-cytokine-stimulated and resting HSCs.

Journal: Blood
Published: June 22, 2014

Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.

Mystery solved: VSV-G-LVs do not allow efficient gene transfer into unstimulated T cells, B cells, and HSCs because they lack the LDL receptor.

Journal: Blood
Published: March 01, 2014

Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.

Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.

Journal: Genesis (New York, N.Y. : 2000)
Published: December 11, 2012

Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.

Stem cell factor-displaying simian immunodeficiency viral vectors together with a low conditioning regimen allow for long-term engraftment of gene-marked autologous hematopoietic stem cells in macaques.

Journal: Human gene therapy
Published: April 03, 2012
Showing 1-12 of 13

Last Updated: 09/26/2026