Diego Benitez

Montevideo, MO, Uruguay

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 28 publications

Insights into the Chemico-Biological Interactions of Natural Sesquiterpene Lactones with the Thiol-Redox Metabolism of Pathogenic Trypanosomatids.

Insights into the Chemico-Biological Interactions of Natural Sesquiterpene Lactones with the Thiol-Redox Metabolism of Pathogenic Trypanosomatids.

Journal: ChemMedChem

Published: July 20, 2025

Restyling an old scaffold: Ebsulfur analogs with improved activity and selectivity against the infective stage of trypanosomes.

Restyling an old scaffold: Ebsulfur analogs with improved activity and selectivity against the infective stage of trypanosomes.

Journal: European journal of medicinal chemistry

Published: February 21, 2025

Looking for approved-medicines to be repositioned as anti-Trypanosoma cruzi agents. Identification of new chemotypes with good individual- or in combination-biological behaviours.

Looking for approved-medicines to be repositioned as anti-Trypanosoma cruzi agents. Identification of new chemotypes with good individual- or in combination-biological behaviours.

Journal: Memorias do Instituto Oswaldo Cruz

Published: August 15, 2024

Multifunctional Organometallic Compounds Active against Infective Trypanosomes: Ru(II) Ferrocenyl Derivatives with Two Different Bioactive Ligands.

Multifunctional Organometallic Compounds Active against Infective Trypanosomes: Ru(II) Ferrocenyl Derivatives with Two Different Bioactive Ligands.

Journal: Inorganic chemistry

Published: June 11, 2024

The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones.

The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones.

Journal: PloS one

Published: June 07, 2023

Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction-Optimization Strategy Applied to Paullones.

Discovery of Antitrypanosomal Indolylacetamides by a Deconstruction-Optimization Strategy Applied to Paullones.

Journal: ChemMedChem

Published: January 24, 2023

Discovery of novel Leishmania major trypanothione synthetase inhibitors by high-throughput screening.

Discovery of novel Leishmania major trypanothione synthetase inhibitors by high-throughput screening.

Journal: Biochemical and biophysical research communications

Published: November 01, 2022

Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models.

Mode of action of p-quinone derivatives with trypanocidal activity studied by experimental and in silico models.

Journal: European journal of medicinal chemistry

Published: September 16, 2022

A Simple Bioluminescent Assay for the Screening of Cytotoxic Molecules Against the Intracellular Form of Leishmania infantum.

A Simple Bioluminescent Assay for the Screening of Cytotoxic Molecules Against the Intracellular Form of Leishmania infantum.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: July 13, 2022

A Simple, Robust, and Affordable Bioluminescent Assay for Drug Screening Against Infective African Trypanosomes.

A Simple, Robust, and Affordable Bioluminescent Assay for Drug Screening Against Infective African Trypanosomes.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: July 13, 2022

Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening.

Drug-like molecules with anti-trypanothione synthetase activity identified by high throughput screening.

Journal: Journal of enzyme inhibition and medicinal chemistry

Published: March 21, 2022

Nox2-derived superoxide radical is crucial to control acute Trypanosoma cruzi infection.

Nox2-derived superoxide radical is crucial to control acute Trypanosoma cruzi infection.

Journal: Redox biology

Published: June 09, 2021

Showing 1-12 of 28

Last Updated: 09/26/2026