Dietmar J. Manstein

Carl Neuberg Str. 1
Hannover, NI 30625, Germany

Last Updated: 09/26/2026

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Found 60 publications

MYH9 Variant p.(Arg424Gly) Alters Nonmuscle Myosin IIA Contraction, Causing Atypical MYH9-related Disease.

MYH9 Variant p.(Arg424Gly) Alters Nonmuscle Myosin IIA Contraction, Causing Atypical MYH9-related Disease.

Journal: Kidney international reports

Published: October 24, 2025

Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies.

Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies.

Journal: American journal of human genetics

Published: July 17, 2025

Mechanics of blunting of actin-myosin interaction dynamics by the actinopathy-causing mutation E334Q in cytoskeletal γ-actin.

Mechanics of blunting of actin-myosin interaction dynamics by the actinopathy-causing mutation E334Q in cytoskeletal γ-actin.

Journal: The Journal of physiology

Published: July 07, 2025

Disruption of SETD3-mediated histidine-73 methylation by the BWCFF-associated β-actin G74S mutation.

Disruption of SETD3-mediated histidine-73 methylation by the BWCFF-associated β-actin G74S mutation.

Journal: FEBS letters

Published: April 11, 2025

Structure of the human nonmuscle myosin 2A motor domain: Insights into isoform-specific mechanochemistry.

Structure of the human nonmuscle myosin 2A motor domain: Insights into isoform-specific mechanochemistry.

Journal: The Journal of biological chemistry

Published: April 11, 2025

Sarcomeric remodelling in human heart failure unraveled by single molecule long read sequencing.

Sarcomeric remodelling in human heart failure unraveled by single molecule long read sequencing.

Journal: EMBO molecular medicine

Published: February 28, 2025

Crystal structures of cables formed by the acetylated and unacetylated forms of the Schizosaccharomyces pombe tropomyosin ortholog TpmCdc8.

Crystal structures of cables formed by the acetylated and unacetylated forms of the Schizosaccharomyces pombe tropomyosin ortholog TpmCdc8.

Journal: The Journal of biological chemistry

Published: July 26, 2024

Cardiac dysfunction related to cardiac mRNA and protein traffic impairment due to reduced unconventional motor protein myosin-5b expression.

Cardiac dysfunction related to cardiac mRNA and protein traffic impairment due to reduced unconventional motor protein myosin-5b expression.

Journal: European heart journal

Published: June 17, 2024

Molecular mechanisms of hotspot variants in cytoskeletal β-actin associated with Baraitser-Winter syndrome.

Molecular mechanisms of hotspot variants in cytoskeletal β-actin associated with Baraitser-Winter syndrome.

Journal: The FEBS journal

Published: April 24, 2024

The non-muscle actinopathy-associated mutation E334Q in cytoskeletal γ-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins.

The non-muscle actinopathy-associated mutation E334Q in cytoskeletal γ-actin perturbs interaction of actin filaments with myosin and ADF/cofilin family proteins.

Journal: eLife

Published: March 06, 2024

Motor properties of Myosin 5c are modulated by tropomyosin isoforms and inhibited by pentabromopseudilin.

Motor properties of Myosin 5c are modulated by tropomyosin isoforms and inhibited by pentabromopseudilin.

Journal: Frontiers in physiology

Published: February 29, 2024

Biochemical characterization of cardiac α-actin mutations A21V and D26N implicated in hypertrophic cardiomyopathy.

Biochemical characterization of cardiac α-actin mutations A21V and D26N implicated in hypertrophic cardiomyopathy.

Journal: Cytoskeleton (Hoboken, N.J.)

Published: December 21, 2023

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Last Updated: 09/26/2026