Dominik Thimm

Bonn, NW 53121, Germany

Last Updated: 09/26/2026

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Found 15 publications

From Inhibitor to Reporter: Nirmatrelvir-Derived Fluorogenic Substrates for the SARS-CoV-2 Main Protease.

From Inhibitor to Reporter: Nirmatrelvir-Derived Fluorogenic Substrates for the SARS-CoV-2 Main Protease.

Journal: ACS chemical biology

Published: June 16, 2026

Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in human mast cells and disease models.

Subnanomolar MAS-related G protein-coupled receptor-X2/B2 antagonists with efficacy in human mast cells and disease models.

Journal: Signal transduction and targeted therapy

Published: August 14, 2024

MAS-related G protein-coupled receptors X (MRGPRX): Orphan GPCRs with potential as targets for future drugs.

MAS-related G protein-coupled receptors X (MRGPRX): Orphan GPCRs with potential as targets for future drugs.

Journal: Pharmacology & therapeutics

Published: May 30, 2022

A Cellular Assay for the Identification and Characterization of Connexin Gap Junction Modulators.

A Cellular Assay for the Identification and Characterization of Connexin Gap Junction Modulators.

Journal: International journal of molecular sciences

Published: January 14, 2021

Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors.

Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors.

Journal: Angewandte Chemie (International ed. in English)

Published: December 21, 2020

A group of cationic amphiphilic drugs activates MRGPRX2 and induces scratching behavior in mice.

A group of cationic amphiphilic drugs activates MRGPRX2 and induces scratching behavior in mice.

Journal: The Journal of allergy and clinical immunology

Published: April 28, 2020

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84.

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84.

Journal: Journal of medicinal chemistry

Published: April 14, 2017

The 2016 Frontiers in Medicinal Chemistry Conference in Bonn.

The 2016 Frontiers in Medicinal Chemistry Conference in Bonn.

Journal: ChemMedChem

Published: January 04, 2017

The nucleobase adenine as a signalling molecule in the kidney.

The nucleobase adenine as a signalling molecule in the kidney.

Journal: Acta physiologica (Oxford, England)

Published: November 13, 2014

6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35.

6-Bromo-8-(4-[(3)H]methoxybenzamido)-4-oxo-4H-chromene-2-carboxylic Acid: a powerful tool for studying orphan G protein-coupled receptor GPR35.

Journal: Journal of medicinal chemistry

Published: July 30, 2013

8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35.

8-Benzamidochromen-4-one-2-carboxylic acids: potent and selective agonists for the orphan G protein-coupled receptor GPR35.

Journal: Journal of medicinal chemistry

Published: May 30, 2013

The second extracellular loop of GPCRs determines subtype-selectivity and controls efficacy as evidenced by loop exchange study at A2 adenosine receptors.

The second extracellular loop of GPCRs determines subtype-selectivity and controls efficacy as evidenced by loop exchange study at A2 adenosine receptors.

Journal: Biochemical pharmacology

Published: January 18, 2013

Showing 1-12 of 15

Last Updated: 09/26/2026