Dominique J. Brees
Basel, BS, Switzerland
Last Updated: 09/26/2026
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Found 26 publications
Erratum: Impact of pre-existing immunity on safety and biodistribution of a single AAV9 vector intrathecal injection in cynomolgus monkeys.
Journal: Molecular therapy. Advances
Published: May 15, 2026
Impact of pre-existing immunity on safety and biodistribution of a single AAV9 vector intrathecal injection in cynomolgus monkeys.
Journal: Molecular therapy. Methods & clinical development
Published: July 10, 2025
Assessment of antigen-specific T cell recall responses in non-human primates using a composite AIM assay.
Journal: Frontiers in immunology
Published: July 07, 2025
Innovative Medicines Initiative public-private partnerships to enhance translational safety.
Journal: Nature reviews. Drug discovery
Published: May 22, 2025
Characterizing Antisense Oligonucleotide-Induced Histopathology Findings in Spinal Cord of Mauritius Cynomolgus Monkeys by Molecular Localization Investigation.
Journal: Toxicologic pathology
Published: January 30, 2025
The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project).
Journal: Toxicology
Published: September 10, 2024
Digital quantitation of bridging fibrosis and septa reveals changes in natural history and treatment not seen with conventional histology.
Journal: Liver international : official journal of the International Association for the Study of the Liver
Published: March 26, 2024
Neurofilament Light Chain: A Translational Safety Biomarker for Drug-Induced Peripheral Neurotoxicity.
Journal: Toxicologic pathology
Published: July 13, 2023
Patients with naproxen-induced liver injury display T-cell memory responses toward an oxidative (S)-O-desmethyl naproxen metabolite but not the acyl glucuronide.
Journal: Allergy
Published: March 24, 2023
Anti-brolucizumab immune response as one prerequisite for rare retinal vasculitis/retinal vascular occlusion adverse events.
Journal: Science translational medicine
Published: February 01, 2023
A root cause analysis to identify the mechanistic drivers of immunogenicity against the anti-VEGF biotherapeutic brolucizumab.
Journal: Science translational medicine
Published: February 01, 2023
Effect of ofatumumab on pregnancy, parturition, and lactation in cynomolgus monkeys.
Journal: Reproductive toxicology (Elmsford, N.Y.)
Published: October 19, 2021
Last Updated: 09/26/2026