Donald J. Graham

Rome, Italy

Last Updated: 09/26/2026

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Found 10 publications

Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development.

Review of Doravirine Resistance Patterns Identified in Participants During Clinical Development.

Journal: Journal of acquired immune deficiency syndromes (1999)

Published: September 14, 2020

HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal.

HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal.

Journal: JCI insight

Published: January 17, 2017

P2-quinazolinones and bis-macrocycles as new templates for next-generation hepatitis C virus NS3/4a protease inhibitors: discovery of MK-2748 and MK-6325.

P2-quinazolinones and bis-macrocycles as new templates for next-generation hepatitis C virus NS3/4a protease inhibitors: discovery of MK-2748 and MK-6325.

Journal: ChemMedChem

Published: December 23, 2014

Discovery of MK-8742: an HCV NS5A inhibitor with broad genotype activity.

Discovery of MK-8742: an HCV NS5A inhibitor with broad genotype activity.

Journal: ChemMedChem

Published: August 22, 2013

Emergence of resistance-associated variants after failed triple therapy with vaniprevir in treatment-experienced non-cirrhotic patients with hepatitis C-genotype 1 infection: a population and clonal analysis.

Emergence of resistance-associated variants after failed triple therapy with vaniprevir in treatment-experienced non-cirrhotic patients with hepatitis C-genotype 1 infection: a population and clonal analysis.

Journal: Virology

Published: March 26, 2013

Antiviral activity of boceprevir monotherapy in treatment-naive subjects with chronic hepatitis C genotype 2/3.

Antiviral activity of boceprevir monotherapy in treatment-naive subjects with chronic hepatitis C genotype 2/3.

Journal: Journal of hepatology

Published: October 03, 2012

Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers.

Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers.

Journal: Bioorganic & medicinal chemistry letters

Published: July 06, 2012

Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease.

Development of potent macrocyclic inhibitors of genotype 3a HCV NS3/4A protease.

Journal: Bioorganic & medicinal chemistry letters

Published: July 06, 2012

MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants.

MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants.

Journal: Antimicrobial agents and chemotherapy

Published: May 23, 2012

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor.

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor.

Journal: ACS medicinal chemistry letters

Published: January 19, 2012

Showing 1-10 of 10

Last Updated: 09/26/2026